ClinVar Miner

Variants in gene combination HRAS, LRRC56 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
110 36 0 26 9 0 1 33

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 15 0 0 0
likely pathogenic 15 0 1 0 0
uncertain significance 0 1 0 8 4
likely benign 0 0 8 0 11
benign 0 0 4 11 0

All variants with conflicting interpretations #

Total variants: 33
Download table as spreadsheet
HGVS dbSNP
NM_005343.2(HRAS):c.34G>T (p.Gly12Cys) rs104894229
NM_005343.2(HRAS):c.35G>A (p.Gly12Asp) rs104894230
NM_005343.2(HRAS):c.35G>C (p.Gly12Ala) rs104894230
NM_005343.2(HRAS):c.35G>T (p.Gly12Val) rs104894230
NM_005343.2(HRAS):c.367C>T (p.Arg123Cys) rs369106578
NM_005343.2(HRAS):c.38G>T (p.Gly13Val) rs104894226
NM_005343.2(HRAS):c.64C>A (p.Gln22Lys) rs121917757
NM_005343.2(HRAS):c.96C>T (p.Tyr32=) rs369039481
NM_005343.3(HRAS):c.*1C>T rs730880327
NM_005343.3(HRAS):c.177C>T (p.Ala59=) rs730880456
NM_005343.3(HRAS):c.181C>A (p.Gln61Lys) rs28933406
NM_005343.3(HRAS):c.330C>T (p.Pro110=) rs200747280
NM_005343.3(HRAS):c.34G>C (p.Gly12Arg) rs104894229
NM_005343.3(HRAS):c.35_36delGCinsAA (p.Gly12Glu) rs727503094
NM_005343.3(HRAS):c.37G>C (p.Gly13Arg) rs104894228
NM_005343.3(HRAS):c.412G>A (p.Gly138Ser) rs397517142
NM_005343.3(HRAS):c.436G>A (p.Ala146Thr) rs104894231
NM_005343.3(HRAS):c.437C>T (p.Ala146Val) rs121917759
NM_005343.3(HRAS):c.451-5C>G rs370181298
NM_005343.4(HRAS):c.257A>C (p.Asn86Thr) rs138272051
NM_005343.4(HRAS):c.309G>A (p.Val103=) rs575789207
NM_005343.4(HRAS):c.369C>T (p.Arg123=) rs200945755
NM_005343.4(HRAS):c.36C>T (p.Gly12=) rs727504424
NM_005343.4(HRAS):c.378A>G (p.Glu126=) rs397517140
NM_005343.4(HRAS):c.37G>T (p.Gly13Cys) rs104894228
NM_005343.4(HRAS):c.477G>A (p.Leu159=) rs140060409
NM_005343.4(HRAS):c.508A>T (p.Lys170Ter) rs372936166
NM_005343.4(HRAS):c.510G>A (p.Lys170=) rs397517143
NM_005343.4(HRAS):c.520C>T (p.Pro174Ser) rs397517144
NM_005343.4(HRAS):c.81T>C (p.His27=) rs12628
NM_176795.4(HRAS):c.182A>G (p.Gln61Arg) rs121913233
NM_176795.4(HRAS):c.277A>G (p.Ile93Val) rs587782949
NM_176795.4(HRAS):c.34G>A (p.Gly12Ser) rs104894229

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