ClinVar Miner

Variants in gene INPP5E with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
103 6 0 20 8 0 1 28

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 1 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 1 0 0 7 2
likely benign 0 0 7 0 19
benign 0 0 2 19 0

All variants with conflicting interpretations #

Total variants: 28
Download table as spreadsheet
HGVS dbSNP
NM_019892.4(INPP5E):c.1132C>T (p.Arg378Cys) rs121918130
NM_019892.4(INPP5E):c.1730C>G (p.Pro577Arg) rs147967974
NM_019892.5(INPP5E):c.-31G>C rs554931078
NM_019892.5(INPP5E):c.1159+7_1159+8insTGGCTGGAGGGGTGGGCG rs71269007
NM_019892.5(INPP5E):c.1159+8C>T rs73566945
NM_019892.5(INPP5E):c.1248T>C (p.Thr416=) rs10781542
NM_019892.5(INPP5E):c.1284T>C (p.Gly428=) rs10870194
NM_019892.5(INPP5E):c.1299G>A (p.Ala433=) rs56931633
NM_019892.5(INPP5E):c.1359C>T (p.Pro453=) rs35774078
NM_019892.5(INPP5E):c.1380C>T (p.Ser460=) rs145543466
NM_019892.5(INPP5E):c.1388-13C>T rs78828148
NM_019892.5(INPP5E):c.1506G>A (p.Pro502=) rs74880446
NM_019892.5(INPP5E):c.1521C>T (p.His507=) rs10870188
NM_019892.5(INPP5E):c.1550-14C>T rs181576122
NM_019892.5(INPP5E):c.1743G>A (p.Thr581=) rs368026621
NM_019892.5(INPP5E):c.1770C>T (p.Leu590=) rs143552175
NM_019892.5(INPP5E):c.1791G>A (p.Pro597=) rs10870182
NM_019892.5(INPP5E):c.1791G>C (p.Pro597=) rs10870182
NM_019892.5(INPP5E):c.1794G>T (p.Gly598=) rs33982662
NM_019892.5(INPP5E):c.21T>C (p.Asn7=) rs571588033
NM_019892.5(INPP5E):c.33C>G (p.Ser11=) rs79161998
NM_019892.5(INPP5E):c.531C>A (p.Ala177=) rs58206296
NM_019892.5(INPP5E):c.603C>G (p.Ile201Met) rs36064831
NM_019892.5(INPP5E):c.636C>A (p.Val212=) rs34071122
NM_019892.5(INPP5E):c.791G>A (p.Arg264His) rs202197173
NM_019892.5(INPP5E):c.944C>T (p.Pro315Leu) rs754637179
NM_019892.5(INPP5E):c.972A>G (p.Pro324=) rs10870199
NM_019892.5(INPP5E):c.981C>T (p.Ala327=) rs35498378

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