ClinVar Miner

Variants in gene ITGA2B with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
203 15 0 12 3 1 2 18

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign association
pathogenic 0 8 2 0 0 0
likely pathogenic 8 0 0 0 0 0
uncertain significance 2 0 0 2 1 0
likely benign 0 0 2 0 4 0
benign 0 0 1 4 0 1
association 0 0 0 0 1 0

All variants with conflicting interpretations #

Total variants: 18
Download table as spreadsheet
NM_000419.3(ITGA2B):c.1787T>C rs76811038
NM_000419.3(ITGA2B):c.439C>G rs76066357
NM_000419.5(ITGA2B):c.1073G>A (p.Arg358His) rs137852908
NM_000419.5(ITGA2B):c.1346G>A (p.Gly449Asp) rs1598380253
NM_000419.5(ITGA2B):c.1627C>T (p.Arg543Trp) rs143967758
NM_000419.5(ITGA2B):c.1878G>C (p.Gln626His) rs80277041
NM_000419.5(ITGA2B):c.1946+1G>A rs746091910
NM_000419.5(ITGA2B):c.207C>T (p.Gly69=) rs375882355
NM_000419.5(ITGA2B):c.2333A>C (p.Gln778Pro) rs74475415
NM_000419.5(ITGA2B):c.2344C>T (p.Arg782Ter) rs1598377051
NM_000419.5(ITGA2B):c.2602-3C>G rs763330792
NM_000419.5(ITGA2B):c.2614C>A (p.Leu872Met) rs149468422
NM_000419.5(ITGA2B):c.2621T>G (p.Ile874Ser) rs5911
NM_000419.5(ITGA2B):c.2870C>T (p.Ser957Leu) rs80002943
NM_000419.5(ITGA2B):c.2916G>A (p.Pro972=) rs5913
NM_000419.5(ITGA2B):c.2965G>A (p.Ala989Thr) rs78165611
NM_000419.5(ITGA2B):c.3076C>T (p.Arg1026Trp) rs766503255
NM_000419.5(ITGA2B):c.891+12del rs373578804

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