ClinVar Miner

Variants in gene LRP4 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
171 22 0 11 6 0 2 18

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 2 0 0
likely pathogenic 1 0 1 0 0
uncertain significance 2 1 0 5 1
likely benign 0 0 5 0 10
benign 0 0 1 10 0

All variants with conflicting interpretations #

Total variants: 18
Download table as spreadsheet
HGVS dbSNP
NM_002334.4(LRP4):c.1048+7G>T rs148557097
NM_002334.4(LRP4):c.1117C>T (p.Arg373Trp) rs118009068
NM_002334.4(LRP4):c.129C>G (p.Thr43=) rs61742974
NM_002334.4(LRP4):c.1501A>C (p.Asn501His) rs72897663
NM_002334.4(LRP4):c.1695G>A (p.Glu565=) rs61741501
NM_002334.4(LRP4):c.300G>A (p.Ser100=) rs61745166
NM_002334.4(LRP4):c.3557G>C (p.Trp1186Ser) rs387906883
NM_002334.4(LRP4):c.3620A>G (p.Asn1207Ser) rs151234321
NM_002334.4(LRP4):c.3830G>A (p.Arg1277His) rs746136135
NM_002334.4(LRP4):c.3944C>T (p.Ser1315Leu) rs150681693
NM_002334.4(LRP4):c.3945G>A (p.Ser1315=) rs61733844
NM_002334.4(LRP4):c.4837+10C>T rs74806847
NM_002334.4(LRP4):c.5165T>A (p.Leu1722His) rs117936904
NM_002334.4(LRP4):c.5520T>C (p.His1840=) rs144350829
NM_002334.4(LRP4):c.639C>T (p.Asp213=) rs144974139
NM_002334.4(LRP4):c.813G>A (p.Thr271=) rs879721
NM_002334.4(LRP4):c.941T>C (p.Leu314Ser) rs7926667
NM_002334.4(LRP4):c.997G>A (p.Gly333Arg) rs61744209

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.