ClinVar Miner

Variants in gene MAP2K2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
250 51 0 28 18 0 1 47

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 3 0 0 0
likely pathogenic 3 0 1 0 0
uncertain significance 0 1 0 17 1
likely benign 0 0 17 0 25
benign 0 0 1 25 0

All variants with conflicting interpretations #

Total variants: 47
Download table as spreadsheet
HGVS dbSNP
NM_030662.3(MAP2K2):c.*8C>T rs377675706
NM_030662.3(MAP2K2):c.181A>G (p.Lys61Glu) rs730880517
NM_030662.3(MAP2K2):c.240G>A (p.Ala80=) rs543217722
NM_030662.3(MAP2K2):c.274A>G (p.Arg92Gly) rs759061964
NM_030662.3(MAP2K2):c.291C>A (p.Ile97=) rs200918323
NM_030662.3(MAP2K2):c.395G>A (p.Gly132Asp) rs387906800
NM_030662.3(MAP2K2):c.450+17C>T rs199892711
NM_030662.3(MAP2K2):c.529-10T>C rs551098822
NM_030662.3(MAP2K2):c.529-15C>T rs778783152
NM_030662.3(MAP2K2):c.529-5T>C rs766943752
NM_030662.3(MAP2K2):c.546G>A (p.Ala182=) rs141402203
NM_030662.3(MAP2K2):c.580+15G>A rs370921720
NM_030662.3(MAP2K2):c.581-9C>T rs539611844
NM_030662.3(MAP2K2):c.787G>A (p.Gly263Arg) rs730880522
NM_030662.3(MAP2K2):c.818A>G (p.Lys273Arg) rs539555837
NM_030662.3(MAP2K2):c.825G>A (p.Leu275=) rs587781027
NM_030662.3(MAP2K2):c.847G>T (p.Val283Leu) rs185999703
NM_030662.3(MAP2K2):c.919+10G>A rs780890887
NM_030662.3(MAP2K2):c.919+10_919+12delinsAAG rs1064794489
NM_030662.3(MAP2K2):c.919+4C>T rs763424788
NM_030662.4(MAP2K2):c.1065G>A (p.Ala355=) rs374807671
NM_030662.4(MAP2K2):c.1093-6T>C rs369681843
NM_030662.4(MAP2K2):c.1140C>T (p.Ala380=) rs146618055
NM_030662.4(MAP2K2):c.1162C>T (p.Arg388Trp) rs144383241
NM_030662.4(MAP2K2):c.1187C>T (p.Thr396Met) rs117945277
NM_030662.4(MAP2K2):c.1194C>T (p.Thr398=) rs144850779
NM_030662.4(MAP2K2):c.246C>T (p.Asn82=) rs150942310
NM_030662.4(MAP2K2):c.281C>T (p.Ser94Leu) rs202220799
NM_030662.4(MAP2K2):c.303+12G>A rs376432107
NM_030662.4(MAP2K2):c.33G>A (p.Ala11=) rs368233443
NM_030662.4(MAP2K2):c.400T>C (p.Tyr134His) rs121434499
NM_030662.4(MAP2K2):c.450+14G>A rs397517414
NM_030662.4(MAP2K2):c.498C>T (p.Pro166=) rs139404261
NM_030662.4(MAP2K2):c.525C>T (p.Ile175=) rs150833333
NM_030662.4(MAP2K2):c.529-12G>A rs375701469
NM_030662.4(MAP2K2):c.580+6G>A rs201435249
NM_030662.4(MAP2K2):c.581-8G>A rs369262004
NM_030662.4(MAP2K2):c.603C>T (p.Leu201=) rs148291450
NM_030662.4(MAP2K2):c.621G>A (p.Glu207=) rs397517416
NM_030662.4(MAP2K2):c.678C>T (p.Ser226=) rs200874968
NM_030662.4(MAP2K2):c.705+11G>A rs202086678
NM_030662.4(MAP2K2):c.806C>G (p.Pro269Arg) rs368064728
NM_030662.4(MAP2K2):c.823C>T (p.Leu275=) rs145934142
NM_030662.4(MAP2K2):c.844C>T (p.Pro282Ser) rs142307980
NM_030662.4(MAP2K2):c.853G>A (p.Asp285Asn) rs150369301
NM_030662.4(MAP2K2):c.860AAG[1] (p.Glu288del) rs763469132
NM_030662.4(MAP2K2):c.93-6C>T rs727504836

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.