ClinVar Miner

Variants in gene MEGF10 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
176 23 0 19 18 0 1 31

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

likely pathogenic uncertain significance likely benign benign
likely pathogenic 0 1 0 0
uncertain significance 1 0 13 12
likely benign 0 13 0 19
benign 0 12 19 0

All variants with conflicting interpretations #

Total variants: 31
Download table as spreadsheet
HGVS dbSNP
NM_032446.2(MEGF10):c.*4C>G rs73783802
NM_032446.2(MEGF10):c.-18-11C>T rs138523651
NM_032446.2(MEGF10):c.1002C>T (p.His334=) rs142947482
NM_032446.2(MEGF10):c.1046G>A (p.Arg349His) rs78847357
NM_032446.2(MEGF10):c.1130+3G>A rs115184652
NM_032446.2(MEGF10):c.116+10T>C rs10519949
NM_032446.2(MEGF10):c.117-5_117-4insC rs538399152
NM_032446.2(MEGF10):c.1500G>A (p.Gln500=) rs146075981
NM_032446.2(MEGF10):c.1564G>A (p.Gly522Arg) rs140563851
NM_032446.2(MEGF10):c.1602C>T (p.Tyr534=) rs114704569
NM_032446.2(MEGF10):c.174G>A (p.Thr58=) rs12654455
NM_032446.2(MEGF10):c.1785T>C (p.Pro595=) rs11950427
NM_032446.2(MEGF10):c.1841-5T>C rs372378202
NM_032446.2(MEGF10):c.2175C>T (p.Ser725=) rs558369303
NM_032446.2(MEGF10):c.2199C>T (p.Cys733=) rs35591368
NM_032446.2(MEGF10):c.2442T>C (p.Thr814=) rs370850456
NM_032446.2(MEGF10):c.2463C>T (p.Pro821=) rs139929890
NM_032446.2(MEGF10):c.2654G>A (p.Gly885Glu) rs116500162
NM_032446.2(MEGF10):c.2857-2A>G rs199750143
NM_032446.2(MEGF10):c.2857-8T>G rs201148765
NM_032446.2(MEGF10):c.3003C>T (p.Ser1001=) rs35159176
NM_032446.2(MEGF10):c.3026-8C>T rs185480820
NM_032446.2(MEGF10):c.303C>T (p.Ser101=) rs77203884
NM_032446.2(MEGF10):c.3215G>A (p.Arg1072Lys) rs17164935
NM_032446.2(MEGF10):c.3387T>A (p.Gly1129=) rs3812052
NM_032446.2(MEGF10):c.489C>T (p.Ile163=) rs34649270
NM_032446.2(MEGF10):c.588G>A (p.Gln196=) rs3812055
NM_032446.2(MEGF10):c.59T>C (p.Ile20Thr) rs748919606
NM_032446.2(MEGF10):c.609C>T (p.Cys203=) rs113794264
NM_032446.2(MEGF10):c.616G>A (p.Val206Ile) rs3812054
NM_032446.2(MEGF10):c.660-3C>T rs6595769

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