ClinVar Miner

Variants in gene MEGF10 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
484 31 0 8 30 0 1 37

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

likely pathogenic uncertain significance likely benign benign
likely pathogenic 0 1 0 0
uncertain significance 1 0 14 17
likely benign 0 14 0 8
benign 0 17 8 0

All variants with conflicting interpretations #

Total variants: 37
Download table as spreadsheet
HGVS dbSNP
NM_001256545.2(MEGF10):c.1002C>T (p.His334=) rs142947482
NM_001256545.2(MEGF10):c.1008C>T (p.Ser336=) rs145815113
NM_001256545.2(MEGF10):c.1046G>A (p.Arg349His) rs78847357
NM_001256545.2(MEGF10):c.1130+3G>A rs115184652
NM_001256545.2(MEGF10):c.117-5_117-4insC rs538399152
NM_001256545.2(MEGF10):c.1500G>A (p.Gln500=) rs146075981
NM_001256545.2(MEGF10):c.1564G>A (p.Gly522Arg) rs140563851
NM_001256545.2(MEGF10):c.1602C>T (p.Tyr534=) rs114704569
NM_001256545.2(MEGF10):c.1626C>T (p.Cys542=) rs146902993
NM_001256545.2(MEGF10):c.1673G>T (p.Arg558Leu) rs182243856
NM_001256545.2(MEGF10):c.1841-5T>C rs372378202
NM_001256545.2(MEGF10):c.1975+10G>A rs148814585
NM_001256545.2(MEGF10):c.2034C>T (p.Asn678=) rs117124929
NM_001256545.2(MEGF10):c.2076C>T (p.Pro692=) rs115309591
NM_001256545.2(MEGF10):c.2157T>C (p.His719=) rs374544972
NM_001256545.2(MEGF10):c.2175C>T (p.Ser725=) rs558369303
NM_001256545.2(MEGF10):c.2176G>A (p.Ala726Thr) rs139884665
NM_001256545.2(MEGF10):c.2199C>T (p.Cys733=) rs35591368
NM_001256545.2(MEGF10):c.2289C>T (p.Asn763=) rs151316424
NM_001256545.2(MEGF10):c.2442T>C (p.Thr814=) rs370850456
NM_001256545.2(MEGF10):c.2463C>T (p.Pro821=) rs139929890
NM_001256545.2(MEGF10):c.2654G>A (p.Gly885Glu) rs116500162
NM_001256545.2(MEGF10):c.2757C>T (p.Asn919=) rs36061366
NM_001256545.2(MEGF10):c.2857-2A>G rs199750143
NM_001256545.2(MEGF10):c.2857-8T>G rs201148765
NM_001256545.2(MEGF10):c.2919G>A (p.Val973=) rs770936974
NM_001256545.2(MEGF10):c.3003C>T (p.Ser1001=) rs35159176
NM_001256545.2(MEGF10):c.3026-8C>T rs185480820
NM_001256545.2(MEGF10):c.303C>T (p.Ser101=) rs77203884
NM_001256545.2(MEGF10):c.3162G>A (p.Pro1054=) rs17164938
NM_001256545.2(MEGF10):c.3180A>G (p.Pro1060=) rs144450528
NM_001256545.2(MEGF10):c.3189G>A (p.Glu1063=) rs56157640
NM_001256545.2(MEGF10):c.3216G>C (p.Arg1072Ser) rs75783175
NM_001256545.2(MEGF10):c.489C>T (p.Ile163=) rs34649270
NM_001256545.2(MEGF10):c.522G>A (p.Arg174=) rs201076330
NM_001256545.2(MEGF10):c.609C>T (p.Cys203=) rs113794264
NM_001256545.2(MEGF10):c.984C>T (p.Asn328=) rs35550094

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