ClinVar Miner

Variants in gene MPI with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
150 13 0 8 12 0 0 20

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 4 0 0 0
likely pathogenic 4 0 0 0 0
uncertain significance 0 0 0 11 3
likely benign 0 0 11 0 4
benign 0 0 3 4 0

All variants with conflicting interpretations #

Total variants: 20
Download table as spreadsheet
HGVS dbSNP
NM_002435.3(MPI):c.1049C>T (p.Thr350Met) rs116933453
NM_002435.3(MPI):c.1050G>A (p.Thr350=) rs145431554
NM_002435.3(MPI):c.10C>T (p.Pro4Ser) rs143982014
NM_002435.3(MPI):c.1269G>A (p.Leu423=) rs371664469
NM_002435.3(MPI):c.132G>A (p.Lys44=) rs778577329
NM_002435.3(MPI):c.166dup (p.Arg56fs) rs786204593
NM_002435.3(MPI):c.214A>C (p.Ser72Arg) rs146699267
NM_002435.3(MPI):c.303C>T (p.Leu101=) rs139228075
NM_002435.3(MPI):c.378G>A (p.Pro126=) rs752948071
NM_002435.3(MPI):c.414G>A (p.Met138Ile) rs150217523
NM_002435.3(MPI):c.488-1G>C rs759579169
NM_002435.3(MPI):c.573C>T (p.Ala191=) rs200903491
NM_002435.3(MPI):c.656G>A (p.Arg219Gln) rs104894489
NM_002435.3(MPI):c.671-4T>G rs199719453
NM_002435.3(MPI):c.678C>A (p.Ala226=) rs199972529
NM_002435.3(MPI):c.845-10G>C rs748693066
NM_002435.3(MPI):c.849C>T (p.Cys283=) rs377419930
NM_002435.3(MPI):c.855G>A (p.Glu285=) rs769504650
NM_002435.3(MPI):c.880dup (p.Val294fs) rs1555479351
NM_002435.3(MPI):c.982C>T (p.Arg328Trp) rs117089191

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