ClinVar Miner

Variants in gene MYH11 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
793 70 0 37 39 0 3 65

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 0 0 0
likely pathogenic 1 0 3 0 0
uncertain significance 0 3 0 31 15
likely benign 0 0 31 0 36
benign 0 0 15 36 0

All variants with conflicting interpretations #

Total variants: 65
Download table as spreadsheet
HGVS dbSNP
MYH11:c.503-14_503-12del rs141564071
NM_002474.3(MYH11):c.1017C>T (p.Ser339=) rs112161189
NM_002474.3(MYH11):c.1032A>G (p.Leu344=) rs112474866
NM_002474.3(MYH11):c.1056G>A (p.Ser352=) rs201256839
NM_002474.3(MYH11):c.1202T>C (p.Ile401Thr) rs773998062
NM_002474.3(MYH11):c.1212G>C (p.Gly404=) rs201198815
NM_002474.3(MYH11):c.1249-15G>T rs886051765
NM_002474.3(MYH11):c.12G>A (p.Lys4=) rs112650390
NM_002474.3(MYH11):c.1413C>T (p.Phe471=) rs758885290
NM_002474.3(MYH11):c.1419G>A (p.Gln473=) rs61734198
NM_002474.3(MYH11):c.1502G>A (p.Arg501His) rs144244239
NM_002474.3(MYH11):c.1512C>T (p.Ile504=) rs149630866
NM_002474.3(MYH11):c.1575+7G>A rs754750176
NM_002474.3(MYH11):c.1576-4A>G rs189193825
NM_002474.3(MYH11):c.1732A>G (p.Ile578Val) rs111936548
NM_002474.3(MYH11):c.1848C>T (p.Ala616=) rs112834652
NM_002474.3(MYH11):c.1871G>A (p.Arg624His) rs201991156
NM_002474.3(MYH11):c.1879G>A (p.Gly627Ser) rs563865467
NM_002474.3(MYH11):c.2005C>T (p.Arg669Cys) rs111404182
NM_002474.3(MYH11):c.2049C>T (p.His683=) rs150924100
NM_002474.3(MYH11):c.2075C>T (p.Ala692Val) rs148893135
NM_002474.3(MYH11):c.2112G>A (p.Val704=) rs781085663
NM_002474.3(MYH11):c.2135G>A (p.Arg712Gln) rs267606902
NM_002474.3(MYH11):c.217A>C (p.Lys73Gln) rs147447269
NM_002474.3(MYH11):c.2520+17A>G rs185697714
NM_002474.3(MYH11):c.2541G>A (p.Val847=) rs373920725
NM_002474.3(MYH11):c.2648C>T (p.Ser883Leu) rs35035518
NM_002474.3(MYH11):c.2665A>C (p.Lys889Gln) rs762308378
NM_002474.3(MYH11):c.2802G>A (p.Glu934=) rs138977949
NM_002474.3(MYH11):c.2893G>T (p.Ala965Ser) rs113696032
NM_002474.3(MYH11):c.291C>T (p.Asn97=) rs113363750
NM_002474.3(MYH11):c.2961C>T (p.Ile987=) rs137988790
NM_002474.3(MYH11):c.300C>T (p.Ser100=) rs111662326
NM_002474.3(MYH11):c.3031T>C (p.Leu1011=) rs112861184
NM_002474.3(MYH11):c.3102T>C (p.Ser1034=) rs181744522
NM_002474.3(MYH11):c.3125G>A (p.Arg1042Gln) rs771297865
NM_002474.3(MYH11):c.3168G>A (p.Leu1056=) rs113089286
NM_002474.3(MYH11):c.3291C>T (p.Ala1097=) rs147605116
NM_002474.3(MYH11):c.3293+6G>A rs370658839
NM_002474.3(MYH11):c.3309C>T (p.Ile1103=) rs370854451
NM_002474.3(MYH11):c.3531G>A (p.Thr1177=) rs149980738
NM_002474.3(MYH11):c.3562C>T (p.Arg1188Trp) rs146388001
NM_002474.3(MYH11):c.3651+5T>G rs794727439
NM_002474.3(MYH11):c.3651+5_3651+11delinsG rs371843272
NM_002474.3(MYH11):c.3651+6_3651+11del rs371843272
NM_002474.3(MYH11):c.3652-6C>T rs193922630
NM_002474.3(MYH11):c.3757_3759AAG[3] (p.Lys1256del) rs730880147
NM_002474.3(MYH11):c.3766A>C (p.Lys1256Gln) rs149241435
NM_002474.3(MYH11):c.3816G>A (p.Glu1272=) rs112990531
NM_002474.3(MYH11):c.3828G>A (p.Ala1276=) rs113154524
NM_002474.3(MYH11):c.387A>G (p.Lys129=) rs78754138
NM_002474.3(MYH11):c.405G>A (p.Ser135=) rs375649016
NM_002474.3(MYH11):c.429G>A (p.Lys143=) rs200672270
NM_002474.3(MYH11):c.444C>T (p.His148=) rs569925780
NM_002474.3(MYH11):c.453G>A (p.Pro151=) rs61734199
NM_002474.3(MYH11):c.471C>T (p.Ile157=) rs140267000
NM_002474.3(MYH11):c.503-9T>C rs554607161
NM_002474.3(MYH11):c.546C>T (p.Ala182=) rs113577450
NM_002474.3(MYH11):c.57C>T (p.Asn19=) rs148464745
NM_002474.3(MYH11):c.633+1942T>C rs199755371
NM_002474.3(MYH11):c.708C>T (p.Asn236=) rs768328532
NM_002474.3(MYH11):c.739C>T (p.Arg247Cys) rs150759461
NM_002474.3(MYH11):c.792T>C (p.Tyr264=) rs34341838
NM_002474.3(MYH11):c.914A>G (p.Asn305Ser) rs185661462
NM_002474.3(MYH11):c.987C>T (p.Thr329=) rs4781689

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