ClinVar Miner

Variants in gene MYH3 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
119 64 0 40 24 0 5 67

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 4 4 0 0
likely pathogenic 4 0 1 0 0
uncertain significance 4 1 0 13 13
likely benign 0 0 13 0 36
benign 0 0 13 36 0

All variants with conflicting interpretations #

Total variants: 67
Download table as spreadsheet
HGVS dbSNP
NM_002470.4(MYH3):c.1123G>A (p.Glu375Lys) rs121913621
NM_002470.4(MYH3):c.1385A>G (p.Asp462Gly) rs121913622
NM_002470.4(MYH3):c.1411T>C (p.Tyr471His) rs115742228
NM_002470.4(MYH3):c.1521C>T (p.Ile507=) rs140685610
NM_002470.4(MYH3):c.1581+13A>C rs2285468
NM_002470.4(MYH3):c.1707G>A (p.Val569=) rs371043485
NM_002470.4(MYH3):c.1932C>T (p.Ser644=) rs115612890
NM_002470.4(MYH3):c.1960-17dup rs3216884
NM_002470.4(MYH3):c.1986_1990del (p.Asn662fs) rs771300756
NM_002470.4(MYH3):c.2106C>T (p.Gly702=) rs56259391
NM_002470.4(MYH3):c.2151C>A (p.Gly717=) rs876657
NM_002470.4(MYH3):c.2166-15A>G rs876660
NM_002470.4(MYH3):c.2289+4A>G rs111835858
NM_002470.4(MYH3):c.252G>A (p.Lys84=) rs147410236
NM_002470.4(MYH3):c.2532A>G (p.Ala844=) rs2285469
NM_002470.4(MYH3):c.2610A>G (p.Lys870=) rs56163389
NM_002470.4(MYH3):c.2683-14C>A rs202129717
NM_002470.4(MYH3):c.2683-4T>C rs182229640
NM_002470.4(MYH3):c.2883C>A (p.Thr961=) rs144338240
NM_002470.4(MYH3):c.2916A>G (p.Thr972=) rs2285472
NM_002470.4(MYH3):c.2926-12A>G rs2285473
NM_002470.4(MYH3):c.2926-8C>T rs188588330
NM_002470.4(MYH3):c.2952T>C (p.Ser984=) rs2285474
NM_002470.4(MYH3):c.3008C>T (p.Ala1003Val) rs34088014
NM_002470.4(MYH3):c.3009G>A (p.Ala1003=) rs61735353
NM_002470.4(MYH3):c.3137G>A (p.Arg1046Gln) rs142002449
NM_002470.4(MYH3):c.3138A>C (p.Arg1046=) rs2285475
NM_002470.4(MYH3):c.3139G>A (p.Val1047Ile) rs542491960
NM_002470.4(MYH3):c.3348T>C (p.Ile1116=) rs201626
NM_002470.4(MYH3):c.3462G>A (p.Ala1154=) rs201553125
NM_002470.4(MYH3):c.3479C>T (p.Thr1160Met) rs145080512
NM_002470.4(MYH3):c.349-7C>T rs114366800
NM_002470.4(MYH3):c.3535C>G (p.Leu1179Val) rs375904355
NM_002470.4(MYH3):c.3574G>A (p.Ala1192Thr) rs2285477
NM_002470.4(MYH3):c.3592G>A (p.Ala1198Thr) rs61735358
NM_002470.4(MYH3):c.3594G>A (p.Ala1198=) rs139978727
NM_002470.4(MYH3):c.3726T>C (p.Ser1242=) rs77946261
NM_002470.4(MYH3):c.3729+9C>T rs201955505
NM_002470.4(MYH3):c.3731C>T (p.Ala1244Val) rs140074626
NM_002470.4(MYH3):c.3938C>T (p.Thr1313Ile) rs35230241
NM_002470.4(MYH3):c.4031T>C (p.Leu1344Pro) rs1567553806
NM_002470.4(MYH3):c.4082C>T (p.Ala1361Val) rs140218185
NM_002470.4(MYH3):c.4128C>T (p.Tyr1376=) rs112569418
NM_002470.4(MYH3):c.412G>A (p.Glu138Lys) rs191837780
NM_002470.4(MYH3):c.4155A>G (p.Glu1385=) rs58343499
NM_002470.4(MYH3):c.4172+9C>T rs116028239
NM_002470.4(MYH3):c.4647+6T>G rs375163919
NM_002470.4(MYH3):c.4731C>T (p.Ile1577=) rs2285479
NM_002470.4(MYH3):c.4910C>T (p.Ala1637Val) rs34165480
NM_002470.4(MYH3):c.5109G>A (p.Ala1703=) rs114770362
NM_002470.4(MYH3):c.5254G>A (p.Ala1752Thr) rs34393601
NM_002470.4(MYH3):c.5274G>A (p.Lys1758=) rs377092561
NM_002470.4(MYH3):c.5331C>T (p.Ser1777=) rs200111154
NM_002470.4(MYH3):c.5390G>A (p.Arg1797His) rs138194008
NM_002470.4(MYH3):c.5457+3G>A rs200954595
NM_002470.4(MYH3):c.5457+9dup rs397750512
NM_002470.4(MYH3):c.642+10G>A rs183463746
NM_002470.4(MYH3):c.690C>G (p.Ala230=) rs147148934
NM_002470.4(MYH3):c.699C>T (p.Asn233=) rs16943604
NM_002470.4(MYH3):c.6T>C (p.Ser2=) rs17817203
NM_002470.4(MYH3):c.700G>A (p.Ala234Thr) rs121913623
NM_002470.4(MYH3):c.724_726TCC[1] (p.Ser243del) rs1555527166
NM_002470.4(MYH3):c.736-6A>G rs372079063
NM_002470.4(MYH3):c.774G>A (p.Lys258=) rs16943598
NM_002470.4(MYH3):c.859T>G (p.Phe287Val) rs1567560080
NM_002470.4(MYH3):c.875C>G (p.Ser292Cys) rs139480342
NM_002470.4(MYH3):c.998C>G (p.Thr333Arg) rs1567559562

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.