ClinVar Miner

Variants in gene MYH3 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
269 20 0 24 5 0 3 31

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 3 3 0 0
likely pathogenic 3 0 0 0 0
uncertain significance 3 0 0 3 2
likely benign 0 0 3 0 21
benign 0 0 2 21 0

All variants with conflicting interpretations #

Total variants: 31
Download table as spreadsheet
HGVS dbSNP
NM_002470.4(MYH3):c.1123G>A (p.Glu375Lys) rs121913621
NM_002470.4(MYH3):c.1385A>G (p.Asp462Gly) rs121913622
NM_002470.4(MYH3):c.1960-17dup rs3216884
NM_002470.4(MYH3):c.2015G>A (p.Arg672His) rs121913617
NM_002470.4(MYH3):c.2106C>T (p.Gly702=) rs56259391
NM_002470.4(MYH3):c.2610A>G (p.Lys870=) rs56163389
NM_002470.4(MYH3):c.2683-4T>C rs182229640
NM_002470.4(MYH3):c.2926-8C>T rs188588330
NM_002470.4(MYH3):c.3008C>T (p.Ala1003Val) rs34088014
NM_002470.4(MYH3):c.3009G>A (p.Ala1003=) rs61735353
NM_002470.4(MYH3):c.3479C>T (p.Thr1160Met) rs145080512
NM_002470.4(MYH3):c.349-7C>T rs114366800
NM_002470.4(MYH3):c.3592G>A (p.Ala1198Thr) rs61735358
NM_002470.4(MYH3):c.3726T>C (p.Ser1242=) rs77946261
NM_002470.4(MYH3):c.3938C>T (p.Thr1313Ile) rs35230241
NM_002470.4(MYH3):c.4031T>C (p.Leu1344Pro) rs1567553806
NM_002470.4(MYH3):c.4082C>T (p.Ala1361Val) rs140218185
NM_002470.4(MYH3):c.4128C>T (p.Tyr1376=) rs112569418
NM_002470.4(MYH3):c.4155A>G (p.Glu1385=) rs58343499
NM_002470.4(MYH3):c.4910C>T (p.Ala1637Val) rs34165480
NM_002470.4(MYH3):c.5109G>A (p.Ala1703=) rs114770362
NM_002470.4(MYH3):c.5254G>A (p.Ala1752Thr) rs34393601
NM_002470.4(MYH3):c.5254G>T (p.Ala1752Ser) rs34393601
NM_002470.4(MYH3):c.5457+3G>A rs200954595
NM_002470.4(MYH3):c.690C>G (p.Ala230=) rs147148934
NM_002470.4(MYH3):c.699C>T (p.Asn233=) rs16943604
NM_002470.4(MYH3):c.6T>C (p.Ser2=) rs17817203
NM_002470.4(MYH3):c.736-6A>G rs372079063
NM_002470.4(MYH3):c.774G>A (p.Lys258=) rs16943598
NM_002470.4(MYH3):c.859T>G (p.Phe287Val) rs1567560080
NM_002470.4(MYH3):c.998C>G (p.Thr333Arg) rs1567559562

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.