ClinVar Miner

Variants in gene NEXN with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
151 63 0 14 16 0 6 27

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 2 1 1
likely pathogenic 1 0 5 0 0
uncertain significance 2 5 0 15 8
likely benign 1 0 15 0 13
benign 1 0 8 13 0

All variants with conflicting interpretations #

Total variants: 27
Download table as spreadsheet
HGVS dbSNP
NM_144573.3(NEXN):c.1029G>A (p.Ala343=) rs374260457
NM_144573.3(NEXN):c.1065T>C (p.Asp355=) rs369897647
NM_144573.3(NEXN):c.1252-10T>G rs201019553
NM_144573.3(NEXN):c.1408G>C (p.Glu470Gln) rs35366555
NM_144573.3(NEXN):c.156C>T (p.Asp52=) rs371431782
NM_144573.3(NEXN):c.1618A>G (p.Met540Val) rs201390657
NM_144573.3(NEXN):c.1677_1682delGGAGGA (p.Glu561_Glu562del) rs397517848
NM_144573.3(NEXN):c.1680_1682delGGA (p.Glu562del) rs397517848
NM_144573.3(NEXN):c.1785C>T (p.Asp595=) rs182998780
NM_144573.3(NEXN):c.1918_1922delTACTT (p.Tyr640Thrfs) rs1222794437
NM_144573.3(NEXN):c.1935C>G (p.Phe645Leu) rs794729086
NM_144573.3(NEXN):c.1949_1951delGAG (p.Gly650del) rs397517853
NM_144573.3(NEXN):c.1955A>G (p.Tyr652Cys) rs137853197
NM_144573.3(NEXN):c.249G>A (p.Glu83=) rs372532824
NM_144573.3(NEXN):c.363G>A (p.Thr121=) rs35117963
NM_144573.3(NEXN):c.512T>C (p.Ile171Thr) rs372065024
NM_144573.3(NEXN):c.732C>A (p.Pro244=) rs201171783
NM_144573.3(NEXN):c.733G>A (p.Gly245Arg) rs1166698
NM_144573.3(NEXN):c.777A>G (p.Gln259=) rs375544798
NM_144573.3(NEXN):c.78T>C (p.Leu26=) rs376535223
NM_144573.3(NEXN):c.835C>T (p.Arg279Cys) rs146245480
NM_144573.3(NEXN):c.856C>T (p.Arg286Trp) rs199917913
NM_144573.3(NEXN):c.864+12T>A rs188416492
NM_144573.3(NEXN):c.865-5G>A rs727505353
NM_144573.3(NEXN):c.893C>G (p.Thr298Arg) rs200753280
NM_144573.3(NEXN):c.949A>C (p.Met317Leu) rs559464457
NM_144573.3(NEXN):c.995A>C (p.Glu332Ala) rs201763096

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