ClinVar Miner

Variants in gene OBSCN with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
3393 245 0 127 20 0 1 145

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

likely pathogenic uncertain significance likely benign benign
likely pathogenic 0 1 0 0
uncertain significance 1 0 20 3
likely benign 0 20 0 127
benign 0 3 127 0

All variants with conflicting interpretations #

Total variants: 145
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001386125.1(OBSCN):c.2894G>A (p.Arg965Lys) rs61560753 0.02514
NM_001386125.1(OBSCN):c.144G>A (p.Gln48=) rs114375717 0.01168
NM_001386125.1(OBSCN):c.8610C>G (p.Thr2870=) rs185248802 0.00977
NM_001386125.1(OBSCN):c.9803C>T (p.Ala3268Val) rs113447751 0.00929
NM_001386125.1(OBSCN):c.11521G>A (p.Gly3841Arg) rs56271332 0.00814
NM_001386125.1(OBSCN):c.16699C>T (p.Leu5567=) rs116642293 0.00811
NM_001386125.1(OBSCN):c.11984C>T (p.Pro3995Leu) rs62621834 0.00810
NM_001386125.1(OBSCN):c.21533-1980G>A rs114053815 0.00806
NM_001386125.1(OBSCN):c.19980T>A (p.Ser6660Arg) rs144372515 0.00796
NM_001386125.1(OBSCN):c.21533-2165C>T rs145544878 0.00776
NM_001386125.1(OBSCN):c.21533-1833G>A rs114510676 0.00756
NM_001386125.1(OBSCN):c.21533-2586C>T rs367920745 0.00728
NM_001386125.1(OBSCN):c.6447C>T (p.His2149=) rs138055037 0.00728
NM_001386125.1(OBSCN):c.16233G>A (p.Thr5411=) rs372827129 0.00726
NM_001386125.1(OBSCN):c.3141G>A (p.Ala1047=) rs140550965 0.00725
NM_001386125.1(OBSCN):c.2528G>A (p.Arg843His) rs141921462 0.00724
NM_001386125.1(OBSCN):c.10472T>G (p.Val3491Gly) rs202022683 0.00722
NM_001386125.1(OBSCN):c.7615C>G (p.Leu2539Val) rs201269256 0.00628
NM_001386125.1(OBSCN):c.4017T>C (p.Phe1339=) rs75365769 0.00605
NM_001386125.1(OBSCN):c.4020A>C (p.Gln1340His) rs199523598 0.00605
NM_001386125.1(OBSCN):c.15666G>A (p.Gln5222=) rs111731636 0.00602
NM_001386125.1(OBSCN):c.6403C>T (p.Arg2135Cys) rs114195142 0.00596
NM_001386125.1(OBSCN):c.18698G>A (p.Arg6233His) rs56015866 0.00583
NM_001386125.1(OBSCN):c.20169C>T (p.Asp6723=) rs142093978 0.00531
NM_001386125.1(OBSCN):c.11559G>A (p.Val3853=) rs111402242 0.00529
NM_001386125.1(OBSCN):c.8633T>C (p.Val2878Ala) rs200720682 0.00526
NM_001386125.1(OBSCN):c.2052C>T (p.Phe684=) rs112046759 0.00462
NM_001386125.1(OBSCN):c.5262C>T (p.Asp1754=) rs142188902 0.00434
NM_001386125.1(OBSCN):c.10722T>C (p.His3574=) rs75962730 0.00422
NM_001386125.1(OBSCN):c.1176C>T (p.Arg392=) rs185717159 0.00405
NM_001386125.1(OBSCN):c.20528A>G (p.Tyr6843Cys) rs200385051 0.00398
NM_001386125.1(OBSCN):c.18465C>T (p.Arg6155=) rs114969585 0.00356
NM_001386125.1(OBSCN):c.12634T>C (p.Ser4212Pro) rs147471011 0.00341
NM_001386125.1(OBSCN):c.8625C>T (p.Thr2875=) rs12030528 0.00336
NM_001386125.1(OBSCN):c.21533-1917G>A rs141233508 0.00326
NM_001386125.1(OBSCN):c.9424G>A (p.Ala3142Thr) rs191370080 0.00326
NM_001386125.1(OBSCN):c.11538G>T (p.Leu3846=) rs114473169 0.00324
NM_001386125.1(OBSCN):c.35T>A (p.Phe12Tyr) rs191837710 0.00322
NM_001386125.1(OBSCN):c.17179C>T (p.Arg5727Cys) rs186194072 0.00312
NM_001386125.1(OBSCN):c.11291C>T (p.Ala3764Val) rs55946300 0.00308
NM_001386125.1(OBSCN):c.16397G>A (p.Arg5466His) rs193004966 0.00307
NM_001386125.1(OBSCN):c.21533-2364G>A rs117551232 0.00302
NM_001386125.1(OBSCN):c.6407G>A (p.Arg2136His) rs28603121 0.00294
NM_001386125.1(OBSCN):c.4490G>A (p.Arg1497Gln) rs199874295 0.00291
NM_001386125.1(OBSCN):c.3162C>T (p.Cys1054=) rs12040506 0.00289
NM_001386125.1(OBSCN):c.16333C>G (p.His5445Asp) rs188287808 0.00261
NM_001386125.1(OBSCN):c.11031G>A (p.Pro3677=) rs79290523 0.00256
NM_001386125.1(OBSCN):c.9957C>T (p.Leu3319=) rs114058903 0.00212
NM_001386125.1(OBSCN):c.2342G>A (p.Arg781His) rs144514297 0.00208
NM_001386125.1(OBSCN):c.11457C>T (p.Pro3819=) rs56367754 0.00201
NM_001386125.1(OBSCN):c.9819G>A (p.Val3273=) rs112403932 0.00184
NM_001386125.1(OBSCN):c.21214C>G (p.Arg7072Gly) rs142615706 0.00172
NM_001386125.1(OBSCN):c.2328C>T (p.Tyr776=) rs369447003 0.00172
NM_001386125.1(OBSCN):c.9842G>A (p.Arg3281Gln) rs188024384 0.00162
NM_001386125.1(OBSCN):c.8343C>T (p.His2781=) rs376684253 0.00150
NM_001386125.1(OBSCN):c.23303C>A (p.Pro7768His) rs201092597 0.00149
NM_001386125.1(OBSCN):c.15509G>A (p.Arg5170His) rs56306215 0.00140
NM_001386125.1(OBSCN):c.11061C>T (p.Phe3687=) rs369584483 0.00134
NM_001386125.1(OBSCN):c.20115C>T (p.Gly6705=) rs140147625 0.00124
NM_001386125.1(OBSCN):c.7302C>T (p.Cys2434=) rs369558704 0.00124
NM_001386125.1(OBSCN):c.3288C>T (p.Cys1096=) rs373806868 0.00120
NM_001386125.1(OBSCN):c.4393G>A (p.Glu1465Lys) rs201854668 0.00116
NM_001386125.1(OBSCN):c.11853C>T (p.Cys3951=) rs200826459 0.00114
NM_001386125.1(OBSCN):c.16361A>T (p.Gln5454Leu) rs116329268 0.00108
NM_001386125.1(OBSCN):c.24417C>T (p.Arg8139=) rs499309 0.00105
NM_001386125.1(OBSCN):c.16425C>T (p.Thr5475=) rs373494343 0.00102
NM_001386125.1(OBSCN):c.18062C>T (p.Ala6021Val) rs56359770 0.00093
NM_001386125.1(OBSCN):c.21303C>T (p.Asp7101=) rs56187628 0.00092
NM_001386125.1(OBSCN):c.18705C>A (p.Ala6235=) rs56025664 0.00089
NM_001386125.1(OBSCN):c.17174C>T (p.Ser5725Leu) rs181568906 0.00083
NM_001386125.1(OBSCN):c.16015A>G (p.Thr5339Ala) rs183406337 0.00078
NM_001386125.1(OBSCN):c.20502G>A (p.Lys6834=) rs191140144 0.00078
NM_001386125.1(OBSCN):c.16853A>C (p.Glu5618Ala) rs200399314 0.00076
NM_001386125.1(OBSCN):c.9672G>A (p.Val3224=) rs3795784 0.00074
NM_001386125.1(OBSCN):c.9065A>G (p.Asn3022Ser) rs113202278 0.00072
NM_001386125.1(OBSCN):c.1899C>T (p.Ser633=) rs193175485 0.00069
NM_001386125.1(OBSCN):c.16251C>T (p.Pro5417=) rs117435683 0.00056
NM_001386125.1(OBSCN):c.9040G>C (p.Asp3014His) rs202052558 0.00056
NM_001386125.1(OBSCN):c.24984A>G (p.Ser8328=) rs370699889 0.00046
NM_001386125.1(OBSCN):c.20378T>C (p.Val6793Ala) rs200917956 0.00038
NM_001386125.1(OBSCN):c.15217G>A (p.Glu5073Lys) rs201877667 0.00032
NM_001386125.1(OBSCN):c.19850C>T (p.Ala6617Val) rs191098985 0.00032
NM_001386125.1(OBSCN):c.23350C>T (p.Arg7784Trp) rs369885852 0.00031
NM_001386125.1(OBSCN):c.10115C>T (p.Ala3372Val) rs199933567 0.00026
NM_001386125.1(OBSCN):c.12420C>T (p.Ala4140=) rs199641194 0.00024
NM_001386125.1(OBSCN):c.20021G>A (p.Ser6674Asn) rs376194851 0.00019
NM_001386125.1(OBSCN):c.3099A>G (p.Thr1033=) rs202097101 0.00019
NM_001386125.1(OBSCN):c.12345C>T (p.Leu4115=) rs527943941 0.00018
NM_001386125.1(OBSCN):c.16503A>G (p.Ala5501=) rs370547153 0.00016
NM_001386125.1(OBSCN):c.3185C>T (p.Ser1062Phe) rs200058427 0.00013
NM_001386125.1(OBSCN):c.19991C>A (p.Ala6664Asp) rs758211855 0.00008
NM_001386125.1(OBSCN):c.11282G>A (p.Arg3761His) rs368175234 0.00006
NM_001386125.1(OBSCN):c.15633G>A (p.Glu5211=) rs529583811 0.00006
NM_001386125.1(OBSCN):c.14555C>T (p.Pro4852Leu) rs201366506 0.00004
NM_001386125.1(OBSCN):c.4797G>A (p.Ala1599=) rs372472787 0.00004
NM_001386125.1(OBSCN):c.9499A>G (p.Ile3167Val) rs764679750 0.00004
NM_001386125.1(OBSCN):c.18006C>T (p.Pro6002=) rs534386095 0.00002
NM_001386125.1(OBSCN):c.8582C>T (p.Thr2861Met) rs747262678 0.00001
NM_001386125.1(OBSCN):c.8631C>T (p.Pro2877=) rs781325246 0.00001
NM_001386125.1(OBSCN):c.9172G>A (p.Ala3058Thr) rs1433965473 0.00001
NM_001386125.1(OBSCN):c.10279C>A (p.Leu3427Ile)
NM_001386125.1(OBSCN):c.10633G>A (p.Val3545Met)
NM_001386125.1(OBSCN):c.11034G>C (p.Gln3678His)
NM_001386125.1(OBSCN):c.11041G>A (p.Gly3681Arg) rs200870329
NM_001386125.1(OBSCN):c.12234G>A (p.Leu4078=)
NM_001386125.1(OBSCN):c.12783G>C (p.Glu4261Asp)
NM_001386125.1(OBSCN):c.1692C>T (p.His564=)
NM_001386125.1(OBSCN):c.17438G>A (p.Arg5813His)
NM_001386125.1(OBSCN):c.17537G>A (p.Arg5846Gln)
NM_001386125.1(OBSCN):c.17759G>A (p.Arg5920His)
NM_001386125.1(OBSCN):c.18010G>T (p.Asp6004Tyr)
NM_001386125.1(OBSCN):c.18456C>T (p.Gly6152=)
NM_001386125.1(OBSCN):c.19271C>T (p.Ser6424Leu)
NM_001386125.1(OBSCN):c.19394G>T (p.Gly6465Val)
NM_001386125.1(OBSCN):c.20055C>A (p.His6685Gln)
NM_001386125.1(OBSCN):c.21282G>T (p.Pro7094=) rs372931114
NM_001386125.1(OBSCN):c.21532+3106A>G
NM_001386125.1(OBSCN):c.21532+3123C>T
NM_001386125.1(OBSCN):c.21533-2163C>T
NM_001386125.1(OBSCN):c.21533-2450G>C
NM_001386125.1(OBSCN):c.21533-2508C>T
NM_001386125.1(OBSCN):c.21533-2727G>A
NM_001386125.1(OBSCN):c.21533-2783C>G
NM_001386125.1(OBSCN):c.22155C>G (p.Thr7385=)
NM_001386125.1(OBSCN):c.2279G>A (p.Arg760Gln)
NM_001386125.1(OBSCN):c.23056G>A (p.Glu7686Lys)
NM_001386125.1(OBSCN):c.23281G>C (p.Ala7761Pro)
NM_001386125.1(OBSCN):c.23344T>G (p.Phe7782Val)
NM_001386125.1(OBSCN):c.23385_23386del (p.Ala7795_Ser7796insTer)
NM_001386125.1(OBSCN):c.23838del (p.Ser7947fs)
NM_001386125.1(OBSCN):c.24415C>T (p.Arg8139Cys)
NM_001386125.1(OBSCN):c.24709G>A (p.Val8237Met)
NM_001386125.1(OBSCN):c.25852C>T (p.Arg8618Trp)
NM_001386125.1(OBSCN):c.25956G>A (p.Gly8652=)
NM_001386125.1(OBSCN):c.3040A>T (p.Thr1014Ser)
NM_001386125.1(OBSCN):c.496G>A (p.Ala166Thr)
NM_001386125.1(OBSCN):c.509G>C (p.Arg170Pro)
NM_001386125.1(OBSCN):c.6253C>T (p.His2085Tyr)
NM_001386125.1(OBSCN):c.7046G>A (p.Gly2349Asp)
NM_001386125.1(OBSCN):c.8103T>G (p.Phe2701Leu)
NM_001386125.1(OBSCN):c.8414A>G (p.Glu2805Gly)
NM_001386125.1(OBSCN):c.8913G>A (p.Ala2971=)
NM_001386125.1(OBSCN):c.8997G>A (p.Thr2999=)
NM_001386125.1(OBSCN):c.9336C>T (p.Gly3112=)
NM_001386125.1(OBSCN):c.962A>G (p.Tyr321Cys)

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