ClinVar Miner

Variants in gene PLA2G6 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
131 22 0 13 2 1 9 22

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign association
pathogenic 0 7 6 1 1 1
likely pathogenic 6 0 3 0 0 0
uncertain significance 5 3 0 1 2 0
likely benign 0 0 1 0 6 0
benign 0 0 2 6 0 0

All variants with conflicting interpretations #

Total variants: 22
Download table as spreadsheet
HGVS dbSNP
NM_003560.4(PLA2G6):c.1027G>A (p.Ala343Thr) rs11570680
NM_003560.4(PLA2G6):c.1086C>T (p.Asn362=) rs2413502
NM_003560.4(PLA2G6):c.1117G>A (p.Gly373Arg) rs587784327
NM_003560.4(PLA2G6):c.1501G>C (p.Glu501Gln) rs587784332
NM_003560.4(PLA2G6):c.1613G>A (p.Arg538His) rs535486098
NM_003560.4(PLA2G6):c.1742+12C>T rs11570739
NM_003560.4(PLA2G6):c.1799G>A (p.Arg600Gln) rs149712244
NM_003560.4(PLA2G6):c.1904G>A (p.Arg635Gln) rs387906863
NM_003560.4(PLA2G6):c.2129G>A (p.Arg710His) rs147455037
NM_003560.4(PLA2G6):c.2215G>C (p.Asp739His) rs587784349
NM_003560.4(PLA2G6):c.2239C>T (p.Arg747Trp) rs121908687
NM_003560.4(PLA2G6):c.2277-2A>C rs552606315
NM_003560.4(PLA2G6):c.2340C>T (p.Asn780=) rs138683183
NM_003560.4(PLA2G6):c.2370T>G (p.Tyr790Ter) rs121908680
NM_003560.4(PLA2G6):c.238G>A (p.Ala80Thr) rs121908685
NM_003560.4(PLA2G6):c.386T>C (p.Leu129Pro) rs374746113
NM_003560.4(PLA2G6):c.673C>T (p.His225Tyr) rs587784359
NM_003560.4(PLA2G6):c.87G>A (p.Val29=) rs2267369
NM_003560.4(PLA2G6):c.957G>A (p.Thr319=) rs11570679
NM_003560.4(PLA2G6):c.972G>A (p.Ala324=) rs147755372
NM_003560.4(PLA2G6):c.991G>A (p.Asp331Asn) rs199935023
Single allele

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