ClinVar Miner

Variants in gene PRDM16 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
553 57 0 13 8 0 1 22

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic uncertain significance likely benign benign
pathogenic 0 1 0 0
uncertain significance 1 0 7 1
likely benign 0 7 0 13
benign 0 1 13 0

All variants with conflicting interpretations #

Total variants: 22
Download table as spreadsheet
NM_022114.4(PRDM16):c.100G>A (p.Ala34Thr) rs187194973
NM_022114.4(PRDM16):c.1187-10G>C rs201517837
NM_022114.4(PRDM16):c.1426C>T (p.Pro476Ser) rs188908415
NM_022114.4(PRDM16):c.1709C>T (p.Thr570Met) rs138655327
NM_022114.4(PRDM16):c.171C>T (p.Ser57=) rs369648897
NM_022114.4(PRDM16):c.201G>A (p.Pro67=) rs199614349
NM_022114.4(PRDM16):c.2058G>A (p.Thr686=) rs368426649
NM_022114.4(PRDM16):c.2290G>A (p.Val764Met) rs149333409
NM_022114.4(PRDM16):c.2448C>T (p.Asn816=) rs372189819
NM_022114.4(PRDM16):c.2449G>A (p.Gly817Ser) rs375308440
NM_022114.4(PRDM16):c.2452G>A (p.Gly818Ser) rs201904226
NM_022114.4(PRDM16):c.2506G>A (p.Gly836Ser) rs114204766
NM_022114.4(PRDM16):c.2940-15G>A rs538723120
NM_022114.4(PRDM16):c.3270G>A (p.Thr1090=) rs375314464
NM_022114.4(PRDM16):c.3301G>A (p.Val1101Met) rs201654872
NM_022114.4(PRDM16):c.3366CGA[3] (p.Asp1125dup) rs758774731
NM_022114.4(PRDM16):c.3687T>C (p.Ala1229=) rs188634763
NM_022114.4(PRDM16):c.38-14G>A rs368409902
NM_022114.4(PRDM16):c.429C>T (p.Cys143=) rs150097149
NM_022114.4(PRDM16):c.481A>G (p.Asn161Asp) rs374664141
NM_022114.4(PRDM16):c.553A>G (p.Met185Val) rs376567517
NM_022114.4(PRDM16):c.872C>T (p.Pro291Leu) rs397514744

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