ClinVar Miner

Variants in gene PROM1 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
64 67 0 13 0 0 2 15

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 3 1 0 0
likely pathogenic 3 0 1 0 0
uncertain significance 1 1 0 0 0
likely benign 0 0 0 0 10
benign 0 0 0 10 0

All variants with conflicting interpretations #

Total variants: 15
Download table as spreadsheet
NM_001145847.2(PROM1):c.1090C>T (p.Arg364Cys) rs137853006
NM_001145847.2(PROM1):c.1148_1149AT[1] (p.Ile384fs) rs746174328
NM_001145847.2(PROM1):c.129C>T (p.Thr43=) rs10033086
NM_001145847.2(PROM1):c.1327dup (p.Tyr443fs) rs543698823
NM_001145847.2(PROM1):c.1552-1G>C rs372513650
NM_001145847.2(PROM1):c.15C>T (p.Leu5=) rs10033189
NM_001145847.2(PROM1):c.1741-5C>T rs55708318
NM_001145847.2(PROM1):c.1950C>T (p.Asn650=) rs149028760
NM_001145847.2(PROM1):c.1956+14G>A rs4698436
NM_001145847.2(PROM1):c.228G>A (p.Leu76=) rs76963591
NM_001145847.2(PROM1):c.55T>G (p.Ser19Ala) rs189108830
NM_001145847.2(PROM1):c.577C>G (p.Arg193Gly) rs140872693
NM_001145847.2(PROM1):c.759G>A (p.Ala253=) rs2286455
NM_001145847.2(PROM1):c.841A>C (p.Ser281Arg) rs182096110
NM_006017.2(PROM1):c.2374-4dupC rs34269395

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