ClinVar Miner

Variants in gene RET with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
546 271 13 65 61 7 15 127

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign protective risk factor
pathogenic 0 26 10 5 3 0 1
likely pathogenic 25 0 4 4 1 0 1
uncertain significance 9 4 9 58 17 0 3
likely benign 5 4 58 1 40 1 2
benign 3 1 17 40 4 1 2
protective 0 0 0 1 1 0 0
risk factor 0 1 3 2 2 0 0

All variants with conflicting interpretations #

Total variants: 127
Download table as spreadsheet
HGVS dbSNP
Multiple alleles
NM_020630.4(RET):c.1996A>G (p.Lys666Glu) rs143795581
NM_020630.4(RET):c.1998G>T (p.Lys666Asn) rs146646971
NM_020630.4(RET):c.200G>A (p.Arg67His) rs192489011
NM_020630.4(RET):c.2081G>A (p.Arg694Gln) rs141185224
NM_020630.4(RET):c.2288A>T (p.Asn763Ile) rs199882293
NM_020630.4(RET):c.2543T>A (p.Met848Lys) rs201101792
NM_020630.4(RET):c.2982A>C (p.Lys994Asn) rs199718928
NM_020630.4(RET):c.3116C>T (p.Pro1039Leu) rs79853121
NM_020630.4(RET):c.509C>T (p.Thr170Ile) rs200547906
NM_020630.4(RET):c.539G>A (p.Arg180Gln) rs370736139
NM_020630.5(RET):c.135A= (p.Ala45=) rs1800858
NM_020630.5(RET):c.1942G>A (p.Val648Ile) rs77711105
NM_020630.5(RET):c.2372A>T (p.Tyr791Phe) rs77724903
NM_020630.5(RET):c.2611G>A (p.Val871Ile) rs145170911
NM_020630.5(RET):c.874G>A (p.Val292Met) rs34682185
NM_020975.4(RET):c.1050C>T (p.Thr350=) rs142188675
NM_020975.4(RET):c.1063+9G>A rs765463636
NM_020975.4(RET):c.1095G>A (p.Ser365=) rs201992974
NM_020975.4(RET):c.1118C>T (p.Ala373Val) rs546866208
NM_020975.4(RET):c.1119G>A (p.Ala373=) rs113931414
NM_020975.4(RET):c.1124T>A (p.Leu375Gln) rs142338976
NM_020975.4(RET):c.1157C>T (p.Ala386Val) rs115272158
NM_020975.4(RET):c.1158G>A (p.Ala386=) rs373540097
NM_020975.4(RET):c.1188G>A (p.Ser396=) rs758510657
NM_020975.4(RET):c.1197G>A (p.Pro399=) rs148371113
NM_020975.4(RET):c.1250G>A (p.Arg417His) rs201030628
NM_020975.4(RET):c.1264-4C>T rs587780806
NM_020975.4(RET):c.1264-5C>T rs9282835
NM_020975.4(RET):c.1336G>C (p.Gly446Arg) rs115423919
NM_020975.4(RET):c.1354C>A (p.Leu452Ile) rs151148041
NM_020975.4(RET):c.1437C>T (p.Ala479=) rs576806356
NM_020975.4(RET):c.1465G>A (p.Asp489Asn) rs9282834
NM_020975.4(RET):c.1522+35C>T rs377130948
NM_020975.4(RET):c.1531G>A (p.Glu511Lys) rs201553718
NM_020975.4(RET):c.1649-5T>C rs876658485
NM_020975.4(RET):c.166C>A (p.Leu56Met) rs145633958
NM_020975.4(RET):c.1699G>A (p.Asp567Asn) rs147219360
NM_020975.4(RET):c.1760-12G>A rs377767392
NM_020975.4(RET):c.1826G>A (p.Cys609Tyr) rs77939446
NM_020975.4(RET):c.1826G>T (p.Cys609Phe) rs77939446
NM_020975.4(RET):c.1846_1848delGAG (p.Glu616del) rs377767399
NM_020975.4(RET):c.1852T>C (p.Cys618Arg) rs76262710
NM_020975.4(RET):c.1853G>A (p.Cys618Tyr) rs79781594
NM_020975.4(RET):c.1867G>A (p.Glu623Lys) rs377767402
NM_020975.4(RET):c.1879+14G>A rs532810255
NM_020975.4(RET):c.1888T>C (p.Cys630Arg) rs377767404
NM_020975.4(RET):c.1893C>T (p.Asp631=) rs55846256
NM_020975.4(RET):c.1901G>A (p.Cys634Tyr) rs75996173
NM_020975.4(RET):c.1902C>G (p.Cys634Trp) rs77709286
NM_020975.4(RET):c.1941C>T (p.Ile647=) rs75225191
NM_020975.4(RET):c.1946C>T (p.Ser649Leu) rs148935214
NM_020975.4(RET):c.1947G>A (p.Ser649=) rs377767412
NM_020975.4(RET):c.1998G>C (p.Lys666Asn) rs146646971
NM_020975.4(RET):c.2037C>T (p.Pro679=) rs55862116
NM_020975.4(RET):c.2052G>A (p.Pro684=) rs145122337
NM_020975.4(RET):c.2070C>T (p.Ser690=) rs201550433
NM_020975.4(RET):c.2071G>A (p.Gly691Ser) rs1799939
NM_020975.4(RET):c.2088G>A (p.Ser696=) rs150329150
NM_020975.4(RET):c.2226G>A (p.Thr742=) rs762876946
NM_020975.4(RET):c.2246G>C (p.Arg749Thr) rs34288963
NM_020975.4(RET):c.225G>A (p.Thr75=) rs151267865
NM_020975.4(RET):c.2284+54C>A rs566375223
NM_020975.4(RET):c.2304G>C (p.Glu768Asp) rs78014899
NM_020975.4(RET):c.2304G>T (p.Glu768Asp) rs78014899
NM_020975.4(RET):c.2342A>G (p.Gln781Arg) rs377767416
NM_020975.4(RET):c.2370G>C (p.Leu790Phe) rs75030001
NM_020975.4(RET):c.2393-9C>T rs567543719
NM_020975.4(RET):c.2410G>A (p.Val804Met) rs79658334
NM_020975.4(RET):c.2410G>C (p.Val804Leu) rs79658334
NM_020975.4(RET):c.2427C>T (p.Tyr809=) rs577929869
NM_020975.4(RET):c.2508C>T (p.Ser836=) rs1800862
NM_020975.4(RET):c.2523G>A (p.Pro841=) rs56195026
NM_020975.4(RET):c.2547C>T (p.Gly849=) rs770674650
NM_020975.4(RET):c.2554A>G (p.Ile852Val) rs561276725
NM_020975.4(RET):c.2607+5G>A rs143862573
NM_020975.4(RET):c.262A>G (p.Ile88Val) rs141679950
NM_020975.4(RET):c.2647G>A (p.Ala883Thr) rs377767428
NM_020975.4(RET):c.2647_2648delGCinsTT (p.Ala883Phe) rs377767429
NM_020975.4(RET):c.2671T>G (p.Ser891Ala) rs75234356
NM_020975.4(RET):c.2673G>A (p.Ser891=) rs201620214
NM_020975.4(RET):c.2711C>T (p.Ser904Phe) rs267607011
NM_020975.4(RET):c.2712C>G (p.Ser904=) rs1800863
NM_020975.4(RET):c.2753T>C (p.Met918Thr) rs74799832
NM_020975.4(RET):c.2802-4G>T rs878855061
NM_020975.4(RET):c.2939+6C>T rs181245759
NM_020975.4(RET):c.2944C>T (p.Arg982Cys) rs17158558
NM_020975.4(RET):c.2976G>A (p.Pro992=) rs528823385
NM_020975.4(RET):c.2988G>A (p.Pro996=) rs145798106
NM_020975.4(RET):c.3057G>A (p.Ala1019=) rs369579749
NM_020975.4(RET):c.3112A>G (p.Thr1038Ala) rs201740483
NM_020975.4(RET):c.3142C>T (p.Leu1048Phe) rs774347808
NM_020975.4(RET):c.337+12G>A rs200468424
NM_020975.4(RET):c.337+9G>A rs2435351
NM_020975.4(RET):c.341G>A (p.Arg114His) rs76397662
NM_020975.4(RET):c.361G>A (p.Val121Ile) rs770548816
NM_020975.4(RET):c.432C>T (p.Arg144=) rs756999107
NM_020975.4(RET):c.468C>T (p.Ala156=) rs141290380
NM_020975.4(RET):c.597C>T (p.Asn199=) rs55810667
NM_020975.4(RET):c.624G>T (p.Glu208Asp) rs781750106
NM_020975.4(RET):c.626-4G>A rs775956924
NM_020975.4(RET):c.654G>A (p.Pro218=) rs137928436
NM_020975.4(RET):c.693C>T (p.Arg231=) rs576806329
NM_020975.4(RET):c.785T>C (p.Val262Ala) rs139790943
NM_020975.4(RET):c.833C>A (p.Thr278Asn) rs35118262
NM_020975.4(RET):c.867+4delC rs398124368
NM_020975.4(RET):c.938G>A (p.Arg313Gln) rs77702891
NM_020975.4(RET):c.957C>A (p.Leu319=) rs149926238
NM_020975.5(RET):c.*1969T>C rs3026785
NM_020975.5(RET):c.1013C>T (p.Thr338Ile) rs377767433
NM_020975.5(RET):c.1529C>T (p.Ala510Val) rs201745826
NM_020975.5(RET):c.1539G>A (p.Ala513=) rs761430718
NM_020975.5(RET):c.1642G>A (p.Gly548Ser) rs374461212
NM_020975.5(RET):c.170G>A (p.Arg57Gln) rs779915615
NM_020975.5(RET):c.1859G>A (p.Cys620Tyr) rs77503355
NM_020975.5(RET):c.1900T>C (p.Cys634Arg) rs75076352
NM_020975.5(RET):c.237G>T (p.Arg79=) rs1554817395
NM_020975.5(RET):c.3188-9C>T rs551159582
NM_020975.5(RET):c.405C>T (p.Gly135=) rs142345108
NM_020975.5(RET):c.487C>A (p.Arg163=) rs371153966
NM_020975.5(RET):c.95C>T (p.Ser32Leu) rs76764689
NM_020975.5(RET):c.973G>A (p.Ala325Thr) rs779719517
NM_020975.6(RET):c.1438G>A (p.Glu480Lys) rs537874538
NM_020975.6(RET):c.1825T>C (p.Cys609Arg) rs77558292
NM_020975.6(RET):c.1831T>C (p.Cys611Arg) rs377767391
NM_020975.6(RET):c.1858T>C (p.Cys620Arg) rs77316810
NM_020975.6(RET):c.375C>A (p.Val125=) rs1800859

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