ClinVar Miner

Variants in gene RIN2 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
101 12 0 17 8 0 0 23

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 0 0 0
likely pathogenic 1 0 0 0 0
uncertain significance 0 0 0 8 2
likely benign 0 0 8 0 16
benign 0 0 2 16 0

All variants with conflicting interpretations #

Total variants: 23
Download table as spreadsheet
HGVS dbSNP
NM_001242581.1(RIN2):c.2251dup (p.Leu751fs) rs1568718508
NM_018993.3(RIN2):c.-2862C>T rs183028833
NM_018993.3(RIN2):c.1004C>G (p.Pro335Arg) rs200780805
NM_018993.3(RIN2):c.1045C>T (p.Pro349Ser) rs201486809
NM_018993.3(RIN2):c.1141C>T (p.Arg381Trp) rs199954296
NM_018993.3(RIN2):c.1239G>T (p.Pro413=) rs534193230
NM_018993.3(RIN2):c.1338G>C (p.Arg446=) rs367993633
NM_018993.3(RIN2):c.1425C>A (p.Pro475=) rs188147644
NM_018993.3(RIN2):c.1427C>G (p.Pro476Arg) rs35142632
NM_018993.3(RIN2):c.1642G>A (p.Val548Met) rs181298473
NM_018993.3(RIN2):c.1851C>T (p.Ala617=) rs180817901
NM_018993.3(RIN2):c.1917G>A (p.Leu639=) rs368610064
NM_018993.3(RIN2):c.1927G>A (p.Ala643Thr) rs199603
NM_018993.3(RIN2):c.1966G>A (p.Val656Ile) rs201964534
NM_018993.3(RIN2):c.2069-8G>A rs78124032
NM_018993.3(RIN2):c.2418C>A (p.Thr806=) rs114329888
NM_018993.3(RIN2):c.2501A>T (p.Tyr834Phe) rs183141566
NM_018993.3(RIN2):c.2571G>A (p.Lys857=) rs149821491
NM_018993.3(RIN2):c.347C>T (p.Pro116Leu) rs147968123
NM_018993.3(RIN2):c.628+7G>A rs370585631
NM_018993.3(RIN2):c.629-8A>C rs190569230
NM_018993.3(RIN2):c.77C>T (p.Ser26Leu) rs577973228
NM_018993.3(RIN2):c.965G>A (p.Ser322Asn) rs199693970

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