ClinVar Miner

Variants in gene TARDBP with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
95 7 1 8 2 0 5 14

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 1 5 5 0 0
likely pathogenic 5 0 1 0 0
uncertain significance 5 1 0 1 2
likely benign 0 0 1 0 3
benign 0 0 2 3 0

All variants with conflicting interpretations #

Total variants: 14
Download table as spreadsheet
HGVS dbSNP
NM_007375.3(TARDBP):c.*697G>A rs387906334
NM_007375.3(TARDBP):c.1042G>T (p.Gly348Cys) rs80356733
NM_007375.3(TARDBP):c.1098C>G (p.Ala366=) rs148325203
NM_007375.3(TARDBP):c.1144G>A (p.Ala382Thr) rs367543041
NM_007375.3(TARDBP):c.1147A>G (p.Ile383Val) rs80356740
NM_007375.3(TARDBP):c.1150G>C (p.Gly384Arg) rs797044594
NM_007375.3(TARDBP):c.198T>C (p.Ala66=) rs61730366
NM_007375.3(TARDBP):c.506A>G (p.Asp169Gly) rs80356717
NM_007375.3(TARDBP):c.669C>G (p.Pro223=) rs149517613
NM_007375.3(TARDBP):c.859G>A (p.Gly287Ser) rs80356719
NM_007375.3(TARDBP):c.869G>C (p.Gly290Ala) rs121908395
NM_007375.3(TARDBP):c.87C>T (p.Ser29=) rs201693535
NM_007375.3(TARDBP):c.881G>T (p.Gly294Val) rs80356721
NM_007375.3(TARDBP):c.892G>A (p.Gly298Ser) rs4884357

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