ClinVar Miner

Variants in gene TCIRG1 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
390 25 0 7 17 0 3 26

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 4 1 0 0
likely pathogenic 4 0 3 0 0
uncertain significance 1 3 0 16 2
likely benign 0 0 16 0 3
benign 0 0 2 3 0

All variants with conflicting interpretations #

Total variants: 26
Download table as spreadsheet
HGVS dbSNP
NM_006019.4(TCIRG1):c.1096C>T (p.Arg366Cys) rs148619884
NM_006019.4(TCIRG1):c.117+1G>A rs377303800
NM_006019.4(TCIRG1):c.117+4A>T rs751881962
NM_006019.4(TCIRG1):c.1195C>T (p.Leu399=) rs151180675
NM_006019.4(TCIRG1):c.1213G>A (p.Gly405Arg) rs137853150
NM_006019.4(TCIRG1):c.1213G>C (p.Gly405Arg) rs137853150
NM_006019.4(TCIRG1):c.1227C>T (p.His409=) rs145080707
NM_006019.4(TCIRG1):c.1249G>A (p.Ala417Thr) rs140963213
NM_006019.4(TCIRG1):c.1278A>G (p.Arg426=) rs138527421
NM_006019.4(TCIRG1):c.1297C>T (p.Gln433Ter) rs777785526
NM_006019.4(TCIRG1):c.1515C>T (p.Thr505=) rs34211419
NM_006019.4(TCIRG1):c.1536C>T (p.Tyr512=) rs138049763
NM_006019.4(TCIRG1):c.1615G>A (p.Val539Ile) rs142539969
NM_006019.4(TCIRG1):c.1623G>A (p.Leu541=) rs534950651
NM_006019.4(TCIRG1):c.1800C>T (p.Ala600=) rs145144233
NM_006019.4(TCIRG1):c.197-5C>T rs183885218
NM_006019.4(TCIRG1):c.2119-10C>T rs377606178
NM_006019.4(TCIRG1):c.2163C>T (p.Ile721=) rs145718040
NM_006019.4(TCIRG1):c.2193C>T (p.Thr731=) rs141601593
NM_006019.4(TCIRG1):c.2397C>T (p.His799=) rs141356870
NM_006019.4(TCIRG1):c.2445C>T (p.Gly815=) rs150788130
NM_006019.4(TCIRG1):c.303_309del (p.Glu102fs) rs886048594
NM_006019.4(TCIRG1):c.476G>A (p.Gly159Glu) rs199632510
NM_006019.4(TCIRG1):c.479G>A (p.Gly160Glu) rs186758849
NM_006019.4(TCIRG1):c.826C>T (p.Arg276Trp) rs543099977
NM_006019.4(TCIRG1):c.90C>T (p.Gly30=) rs141859450

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