ClinVar Miner

Variants in gene TMPRSS3 with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
94 14 0 13 9 0 2 22

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 1 1 0 0
likely pathogenic 1 0 1 0 0
uncertain significance 1 1 0 5 6
likely benign 0 0 5 0 12
benign 0 0 6 12 0

All variants with conflicting interpretations #

Total variants: 22
Download table as spreadsheet
HGVS dbSNP
NM_001256317.1(TMPRSS3):c.212T>C (p.Phe71Ser) rs185332310
NM_024022.2(TMPRSS3):c.*2G>A rs13047838
NM_024022.2(TMPRSS3):c.-34G>A rs73372256
NM_024022.2(TMPRSS3):c.-51-7G>C rs4920100
NM_024022.2(TMPRSS3):c.1122C>T (p.Asp374=) rs113747896
NM_024022.2(TMPRSS3):c.1128C>T (p.Tyr376=) rs111033292
NM_024022.2(TMPRSS3):c.1309G>A (p.Val437Ile) rs114904237
NM_024022.2(TMPRSS3):c.1335C>T (p.His445=) rs186972955
NM_024022.2(TMPRSS3):c.157G>A (p.Val53Ile) rs928302
NM_024022.2(TMPRSS3):c.239G>A (p.Arg80His) rs146159479
NM_024022.2(TMPRSS3):c.325C>T (p.Arg109Trp) rs201632198
NM_024022.2(TMPRSS3):c.326G>A (p.Arg109Gln) rs139484231
NM_024022.2(TMPRSS3):c.331G>A (p.Gly111Ser) rs35227181
NM_024022.2(TMPRSS3):c.413C>A (p.Ala138Glu) rs147231991
NM_024022.2(TMPRSS3):c.432A>G (p.Gln144=) rs61731564
NM_024022.2(TMPRSS3):c.447-13A>G rs8130564
NM_024022.2(TMPRSS3):c.453G>A (p.Val151=) rs2839501
NM_024022.2(TMPRSS3):c.497G>T (p.Arg166Leu) rs150397427
NM_024022.2(TMPRSS3):c.617-3_617-2dupTA rs34966432
NM_024022.2(TMPRSS3):c.757A>G (p.Ile253Val) rs2839500
NM_024022.2(TMPRSS3):c.957G>C (p.Met319Ile) rs115223836
NM_024022.2(TMPRSS3):c.975G>T (p.Leu325=) rs397517379

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