ClinVar Miner

Variants in gene TNNI3 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
165 37 0 26 7 1 15 42

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor
pathogenic 0 16 3 0 0 0
likely pathogenic 16 0 15 0 0 0
uncertain significance 3 15 0 7 3 0
likely benign 0 0 7 0 10 1
benign 0 0 3 10 0 1
risk factor 0 0 0 1 1 0

All variants with conflicting interpretations #

Total variants: 42
Download table as spreadsheet
HGVS dbSNP
NM_000363.4(TNNI3):c.12-7delC rs370714315
NM_000363.4(TNNI3):c.139T>C (p.Leu47=) rs587780967
NM_000363.4(TNNI3):c.151-6C>G rs377258542
NM_000363.4(TNNI3):c.198G>A (p.Glu66=) rs3729710
NM_000363.4(TNNI3):c.204delG (p.Arg69Alafs) rs727504872
NM_000363.4(TNNI3):c.235C>T (p.Arg79Cys) rs3729712
NM_000363.4(TNNI3):c.244C>T (p.Pro82Ser) rs77615401
NM_000363.4(TNNI3):c.25-4C>T rs202086705
NM_000363.4(TNNI3):c.294A>G (p.Arg98=)
NM_000363.4(TNNI3):c.302A>G (p.His101Arg) rs730881087
NM_000363.4(TNNI3):c.336C>T (p.Tyr112=) rs559450042
NM_000363.4(TNNI3):c.340A>G (p.Ile114Val) rs730881070
NM_000363.4(TNNI3):c.370G>C (p.Glu124Gln) rs727503506
NM_000363.4(TNNI3):c.372+7C>T rs367809676
NM_000363.4(TNNI3):c.384G>A (p.Leu128=) rs373130533
NM_000363.4(TNNI3):c.407G>A (p.Arg136Gln) rs730881069
NM_000363.4(TNNI3):c.421C>T (p.Arg141Trp) rs730881071
NM_000363.4(TNNI3):c.422G>A (p.Arg141Gln) rs397516347
NM_000363.4(TNNI3):c.428C>A (p.Thr143Asn) rs397516348
NM_000363.4(TNNI3):c.433C>T (p.Arg145Trp) rs104894724
NM_000363.4(TNNI3):c.434G>A (p.Arg145Gln) rs397516349
NM_000363.4(TNNI3):c.451G>A (p.Ala151Thr) rs730881072
NM_000363.4(TNNI3):c.484C>T (p.Arg162Trp) rs368861241
NM_000363.4(TNNI3):c.485G>A (p.Arg162Gln) rs397516354
NM_000363.4(TNNI3):c.485G>C (p.Arg162Pro) rs397516354
NM_000363.4(TNNI3):c.497C>T (p.Ser166Phe) rs727504242
NM_000363.4(TNNI3):c.508C>G (p.Arg170Gly) rs727503504
NM_000363.4(TNNI3):c.508C>T (p.Arg170Trp) rs727503504
NM_000363.4(TNNI3):c.509G>A (p.Arg170Gln) rs727503503
NM_000363.4(TNNI3):c.523C>T (p.Gln175Ter) rs876661394
NM_000363.4(TNNI3):c.526G>A (p.Val176Met) rs727503501
NM_000363.4(TNNI3):c.544G>A (p.Glu182Lys) rs397516355
NM_000363.4(TNNI3):c.550-10C>T rs201240150
NM_000363.4(TNNI3):c.557G>A (p.Arg186Gln) rs397516357
NM_000363.4(TNNI3):c.562G>A (p.Val188Met) rs193922409
NM_000363.4(TNNI3):c.575G>A (p.Arg192His) rs104894729
NM_000363.4(TNNI3):c.586G>A (p.Asp196Asn) rs104894727
NM_000363.4(TNNI3):c.592C>G (p.Leu198Val) rs727504285
NM_000363.4(TNNI3):c.596G>A (p.Ser199Asn) rs730881091
NM_000363.4(TNNI3):c.610C>T (p.Arg204Cys) rs727504243
NM_000363.4(TNNI3):c.611G>A (p.Arg204His) rs727504275
NM_000363.4(TNNI3):c.6G>A (p.Ala2=) rs397516361

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