ClinVar Miner

Variants in gene TRAPPC9 with conflicting interpretations

See also:
Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
690 86 0 46 43 0 3 80

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 4 1 0 0
likely pathogenic 4 0 2 0 0
uncertain significance 1 2 0 42 13
likely benign 0 0 42 0 42
benign 0 0 13 42 0

All variants with conflicting interpretations #

Total variants: 80
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001160372.4(TRAPPC9):c.207T>C (p.Gly69=) rs3735801 0.55959
NM_001160372.4(TRAPPC9):c.288T>C (p.Phe96=) rs3735802 0.55845
NM_001160372.4(TRAPPC9):c.411C>T (p.Asn137=) rs3735803 0.45974
NM_001160372.4(TRAPPC9):c.1692C>T (p.Asn564=) rs12549048 0.22639
NM_001160372.4(TRAPPC9):c.2292C>T (p.Gly764=) rs11166965 0.10684
NM_001160372.4(TRAPPC9):c.2431+7G>A rs11166964 0.10663
NM_001160372.4(TRAPPC9):c.399T>C (p.Ala133=) rs61739560 0.08885
NM_001160372.4(TRAPPC9):c.555G>A (p.Lys185=) rs57593250 0.08881
NM_001160372.4(TRAPPC9):c.357G>A (p.Gly119=) rs34457678 0.08878
NM_001160372.4(TRAPPC9):c.2799= (p.Gly933=) rs2614718 0.08065
NM_001160372.4(TRAPPC9):c.3279+4C>T rs79877357 0.02434
NM_001160372.4(TRAPPC9):c.1982-20A>C rs74414386 0.01477
NM_001160372.4(TRAPPC9):c.2742C>T (p.Thr914=) rs28710457 0.01086
NM_031466.8(TRAPPC9):c.-11+10G>A rs117206975 0.01054
NM_001160372.4(TRAPPC9):c.1869C>T (p.Ser623=) rs117685875 0.01001
NM_001160372.4(TRAPPC9):c.456C>T (p.Ile152=) rs61740786 0.00921
NM_001160372.4(TRAPPC9):c.414C>T (p.Tyr138=) rs115986561 0.00912
NM_001160372.4(TRAPPC9):c.1458C>T (p.Phe486=) rs34179337 0.00827
NM_001160372.4(TRAPPC9):c.584+19C>T rs143903438 0.00701
NM_001160372.4(TRAPPC9):c.2797G>A (p.Gly933Ser) rs114949291 0.00641
NM_001160372.4(TRAPPC9):c.3163G>A (p.Val1055Ile) rs35578974 0.00512
NM_001160372.4(TRAPPC9):c.3249C>T (p.Phe1083=) rs112551069 0.00501
NM_001160372.4(TRAPPC9):c.7G>A (p.Val3Ile) rs76033442 0.00489
NM_001160372.4(TRAPPC9):c.3390A>C (p.Pro1130=) rs143396124 0.00333
NM_031466.8(TRAPPC9):c.-108A>G rs144686266 0.00305
NM_001160372.4(TRAPPC9):c.588T>C (p.His196=) rs61736350 0.00284
NM_001160372.4(TRAPPC9):c.3291C>T (p.Ser1097=) rs148857575 0.00222
NM_001160372.4(TRAPPC9):c.1407C>T (p.Tyr469=) rs117632905 0.00151
NM_001160372.4(TRAPPC9):c.3012C>T (p.Asn1004=) rs148805943 0.00151
NM_001160372.4(TRAPPC9):c.3421G>A (p.Val1141Met) rs140157207 0.00147
NM_001160372.4(TRAPPC9):c.1164C>T (p.Tyr388=) rs148976893 0.00136
NM_001160372.4(TRAPPC9):c.3149G>A (p.Arg1050Gln) rs111768745 0.00103
NM_001160372.4(TRAPPC9):c.159C>T (p.Leu53=) rs112997540 0.00089
NM_001160372.4(TRAPPC9):c.3414T>G (p.Ser1138Arg) rs147127279 0.00089
NM_001160372.4(TRAPPC9):c.3241G>A (p.Val1081Ile) rs141067069 0.00078
NM_001160372.4(TRAPPC9):c.263C>T (p.Ser88Leu) rs139631202 0.00072
NM_001160372.4(TRAPPC9):c.2671A>C (p.Thr891Pro) rs562249191 0.00066
NM_031466.8(TRAPPC9):c.-11+6C>T rs376367358 0.00066
NM_001160372.4(TRAPPC9):c.3175G>A (p.Ala1059Thr) rs150200902 0.00056
NM_001160372.4(TRAPPC9):c.2796C>T (p.Ala932=) rs145607512 0.00038
NM_031466.8(TRAPPC9):c.-135A>G rs148523016 0.00037
NM_001160372.4(TRAPPC9):c.3356G>A (p.Arg1119Gln) rs145503551 0.00034
NM_001160372.4(TRAPPC9):c.1809G>A (p.Leu603=) rs146235874 0.00029
NM_001160372.4(TRAPPC9):c.3411C>A (p.Pro1137=) rs373979305 0.00022
NM_001160372.4(TRAPPC9):c.370A>G (p.Ile124Val) rs117688394 0.00022
NM_001160372.4(TRAPPC9):c.2981G>C (p.Ser994Thr) rs377114410 0.00016
NM_001160372.4(TRAPPC9):c.3136C>T (p.Arg1046Trp) rs376617920 0.00015
NM_001160372.4(TRAPPC9):c.543G>A (p.Pro181=) rs149504969 0.00012
NM_001160372.4(TRAPPC9):c.1194C>T (p.Ile398=) rs587780484 0.00011
NM_001160372.4(TRAPPC9):c.2901G>C (p.Glu967Asp) rs139074311 0.00010
NM_031466.8(TRAPPC9):c.-24G>A rs370984854 0.00009
NM_001160372.4(TRAPPC9):c.2245C>T (p.Leu749=) rs375545861 0.00006
NM_001160372.4(TRAPPC9):c.3055+10C>T rs571622542 0.00006
NM_031466.8(TRAPPC9):c.-73G>C rs767996463 0.00005
NM_001160372.4(TRAPPC9):c.2037G>A (p.Pro679=) rs371880751 0.00004
NM_001160372.4(TRAPPC9):c.2704C>T (p.Arg902Trp) rs370626310 0.00004
NM_001160372.4(TRAPPC9):c.2793C>T (p.His931=) rs886062722 0.00004
NM_001160372.4(TRAPPC9):c.2811-4G>A rs374826041 0.00004
NM_001160372.4(TRAPPC9):c.2811-5C>T rs534788967 0.00004
NM_001160372.4(TRAPPC9):c.3056A>C (p.Asp1019Ala) rs755371528 0.00004
NM_001160372.4(TRAPPC9):c.1414C>T (p.Arg472Ter) rs267607137 0.00003
NM_001160372.4(TRAPPC9):c.1768+7C>T rs587780485 0.00003
NM_001160372.4(TRAPPC9):c.3288G>A (p.Pro1096=) rs570688248 0.00003
NM_001160372.4(TRAPPC9):c.1693G>A (p.Val565Met) rs551407866 0.00002
NM_001160372.4(TRAPPC9):c.2988G>A (p.Glu996=) rs142048892 0.00002
NM_001160372.4(TRAPPC9):c.1560C>T (p.Pro520=) rs886062724 0.00001
NM_001160372.4(TRAPPC9):c.2854G>T (p.Glu952Ter) rs766614772 0.00001
NM_001160372.4(TRAPPC9):c.3148C>T (p.Arg1050Trp) rs563050274 0.00001
NM_001160372.4(TRAPPC9):c.367G>T (p.Glu123Ter) rs587780486 0.00001
NM_001160372.4(TRAPPC9):c.*532G>A rs187594197
NM_001160372.4(TRAPPC9):c.1326G>A (p.Ser442=) rs145960296
NM_001160372.4(TRAPPC9):c.1353C>T (p.Gly451=)
NM_001160372.4(TRAPPC9):c.2279-11del rs758850777
NM_001160372.4(TRAPPC9):c.239T>C (p.Leu80Pro) rs2132705299
NM_001160372.4(TRAPPC9):c.2475G>A (p.Arg825=) rs756688439
NM_001160372.4(TRAPPC9):c.269A>G (p.Lys90Arg) rs550423753
NM_001160372.4(TRAPPC9):c.274_280del (p.Trp92fs) rs1554689964
NM_001160372.4(TRAPPC9):c.3087C>T (p.Arg1029=) rs561829257
NM_001160372.4(TRAPPC9):c.3225C>A (p.Tyr1075Ter) rs58740567
NM_001160372.4(TRAPPC9):c.3225C>T (p.Tyr1075=) rs58740567

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