ClinVar Miner

Variants in gene TSPEAR with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
75 16 0 9 5 0 1 13

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

likely pathogenic uncertain significance likely benign benign
likely pathogenic 0 1 0 0
uncertain significance 1 0 4 3
likely benign 0 4 0 9
benign 0 3 9 0

All variants with conflicting interpretations #

Total variants: 13
Download table as spreadsheet
HGVS dbSNP
NM_144991.3(TSPEAR):c.151G>A (p.Val51Ile) rs150016894
NM_144991.3(TSPEAR):c.169C>T (p.Arg57Trp) rs140542643
NM_144991.3(TSPEAR):c.170G>A (p.Arg57Gln) rs151001222
NM_144991.3(TSPEAR):c.1746C>T (p.Leu582=) rs147258456
NM_144991.3(TSPEAR):c.1915G>A (p.Asp639Asn) rs138480801
NM_144991.3(TSPEAR):c.343G>A (p.Asp115Asn) rs144586270
NM_144991.3(TSPEAR):c.44C>T (p.Ala15Val) rs150107590
NM_144991.3(TSPEAR):c.51C>T (p.Gly17=) rs75351275
NM_144991.3(TSPEAR):c.534G>A (p.Pro178=) rs148713881
NM_144991.3(TSPEAR):c.589C>T (p.Arg197Ter) rs139455627
NM_144991.3(TSPEAR):c.668C>T (p.Ser223Leu) rs149481227
NM_144991.3(TSPEAR):c.702C>T (p.Asn234=) rs117791519
NM_144991.3(TSPEAR):c.714G>A (p.Ala238=) rs146025689

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