ClinVar Miner

Variants in gene TTC21B with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
78 73 0 23 10 0 3 29

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

likely pathogenic uncertain significance likely benign benign
pathogenic 1 1 1 0
likely pathogenic 0 2 0 0
uncertain significance 2 0 10 6
likely benign 0 10 0 22
benign 0 6 22 0

All variants with conflicting interpretations #

Total variants: 29
Download table as spreadsheet
HGVS dbSNP
NM_024753.4(TTC21B):c.114C>G (p.Val38=) rs34486024
NM_024753.4(TTC21B):c.1387C>T (p.Pro463Ser) rs16851307
NM_024753.4(TTC21B):c.1417C>T (p.Leu473Phe) rs2163649
NM_024753.4(TTC21B):c.1495G>A (p.Ala499Thr) rs866222900
NM_024753.4(TTC21B):c.1571C>G (p.Ser524Cys) rs145436538
NM_024753.4(TTC21B):c.1650A>G (p.Glu550=) rs145926679
NM_024753.4(TTC21B):c.1695C>T (p.Tyr565=) rs6750044
NM_024753.4(TTC21B):c.1715C>A (p.Ser572Ter) rs369159801
NM_024753.4(TTC21B):c.1846C>T (p.Arg616Cys) rs139441507
NM_024753.4(TTC21B):c.1870A>G (p.Ile624Val) rs77106136
NM_024753.4(TTC21B):c.2014C>T (p.Arg672Trp) rs140757802
NM_024753.4(TTC21B):c.2175T>C (p.Phe725=) rs10176588
NM_024753.4(TTC21B):c.2211+13A>G rs73969727
NM_024753.4(TTC21B):c.2322+3A>G rs79037278
NM_024753.4(TTC21B):c.2334C>T (p.Tyr778=) rs79656636
NM_024753.4(TTC21B):c.2385G>C (p.Leu795=) rs80225158
NM_024753.4(TTC21B):c.2569-5dupT rs144600502
NM_024753.4(TTC21B):c.2742C>T (p.Cys914=) rs73018799
NM_024753.4(TTC21B):c.3004C>G (p.Leu1002Val) rs146496725
NM_024753.4(TTC21B):c.3519T>C (p.Thr1173=) rs115504901
NM_024753.4(TTC21B):c.3519T>G (p.Thr1173=) rs115504901
NM_024753.4(TTC21B):c.549T>C (p.Gly183=) rs141664029
NM_024753.4(TTC21B):c.601G>A (p.Val201Met) rs1432273
NM_024753.4(TTC21B):c.665A>T (p.Gln222Leu) rs80026831
NM_024753.4(TTC21B):c.691A>T (p.Thr231Ser) rs149925563
NM_024753.4(TTC21B):c.724G>A (p.Asp242Asn) rs74447004
NM_024753.4(TTC21B):c.826A>G (p.Thr276Ala) rs7592429
NM_024753.4(TTC21B):c.838A>G (p.Met280Val) rs112868646
Single allele

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