ClinVar Miner

Variants in gene LRRK2

Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
16 1 205 47 29 1 253

Condition and significance breakdown #

Total conditions: 8
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Condition pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
Parkinson disease 8, autosomal dominant 15 0 193 46 20 1 236
not provided 1 1 15 0 10 0 27
not specified 0 0 2 0 4 0 6
Parkinson disease, late-onset 1 0 2 0 0 0 3
Frontotemporal dementia; Parkinsonism; Rigidity; Brain atrophy 0 0 1 0 0 0 1
Inborn genetic diseases 1 0 0 0 0 0 1
Parkinson Disease, Dominant 0 0 0 1 0 0 1
See cases 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 16
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign risk factor total
GeneReviews 15 0 127 0 0 0 142
Illumina Clinical Services Laboratory,Illumina 0 0 49 40 11 0 100
Invitae 2 0 25 8 9 0 44
Athena Diagnostics Inc 1 0 2 0 14 0 17
OMIM 7 0 0 0 0 1 8
GeneDx 1 1 6 0 0 0 8
CeGaT Praxis fuer Humangenetik Tuebingen 0 0 8 0 0 0 8
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics 0 0 2 0 0 0 2
Neurogenetic Laboratory,Oslo University Hospital 0 0 2 0 0 0 2
Ambry Genetics 1 0 0 0 0 0 1
Courtagen Diagnostics Laboratory,Courtagen Life Sciences 1 0 0 0 0 0 1
Fulgent Genetics 1 0 0 0 0 0 1
Institute of Human Genetics,Klinikum rechts der Isar 1 0 0 0 0 0 1
Zabetian_UW Neurogenetics Lab, University of Washington/VAPSHCS 1 0 0 0 0 0 1
Bioscientia Institut fuer Medizinische Diagnostik GmbH,Sonic Healthcare 1 0 0 0 0 0 1
Centre for Mendelian Genomics,University Medical Centre Ljubljana 0 0 1 0 0 0 1

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