Variants studied for colorectal cancer, hereditary nonpolyposis, type 7

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)
		ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
3	2	784	307	54	1102

Gene and significance breakdown #

Total genes and gene combinations: 3

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
MLH3	2	2	784	304	51	1097
EIF2B2, MLH3	0	0	0	1	2	3
AREL1, MLH3	1	0	0	2	1	2

Submitter and significance breakdown #

Total submitters: 13

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Submitter	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	total
Labcorp Genetics (formerly Invitae), Labcorp	0	0	710	270	47	1027
Illumina Laboratory Services, Illumina	0	0	86	36	15	137
KCCC/NGS Laboratory, Kuwait Cancer Control Center	0	0	4	4	17	25
OMIM	3	0	4	0	0	7
Fulgent Genetics, Fulgent Genetics	0	0	5	2	0	7
Baylor Genetics	0	0	1	0	0	1
Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center	0	1	0	0	0	1
Center for Individualized Medicine, Mayo Clinic	0	1	0	0	0	1
Foundation for Research in Genetics and Endocrinology, FRIGE's Institute of Human Genetics	0	0	1	0	0	1
Equipe Genetique des Anomalies du Developpement, Université de Bourgogne	0	0	1	0	0	1
Institute of Human Genetics, University of Leipzig Medical Center	0	0	0	1	0	1
Neuberg Centre For Genomic Medicine, NCGM	0	0	1	0	0	1
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein	0	0	1	0	0	1

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