ClinVar Miner

Variants studied for adrenal cortex neoplasm

Included ClinVar conditions (11):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
70 156 84 26 4 328

Gene and significance breakdown #

Total genes and gene combinations: 45
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign total
TP53 53 89 46 5 2 183
CLCN2 6 4 16 21 2 49
PIK3CA 0 14 1 0 0 15
CTNNB1, LOC126806658 0 11 0 0 0 11
FBXW7 0 5 0 0 0 5
IDH1 0 5 0 0 0 5
NRAS 0 5 0 0 0 5
CREBBP 0 4 0 0 0 4
ATP1A1 3 0 0 0 0 3
ATP2B3 3 0 0 0 0 3
BCOR 0 3 0 0 0 3
BRAF 0 3 0 0 0 3
GNAS 0 3 0 0 0 3
HRAS, LRRC56 0 3 0 0 0 3
SF3B1 0 3 0 0 0 3
ATRX 0 0 2 0 0 2
BAP1 0 0 2 0 0 2
NOTCH1 0 2 0 0 0 2
ALK 0 0 1 0 0 1
ARID1B 0 0 1 0 0 1
ARID2 0 1 0 0 0 1
ATM 0 0 1 0 0 1
CDKN2C, FAF1 0 0 1 0 0 1
CHEK2 0 0 1 0 0 1
CTNNB1 0 0 1 0 0 1
FGFR2 0 0 1 0 0 1
FUS, TFCP2 0 0 1 0 0 1
H3-3A 0 1 0 0 0 1
INSL6, JAK2 0 0 1 0 0 1
JAK3 0 0 1 0 0 1
KMT2A 0 0 1 0 0 1
KRAS 1 0 0 0 0 1
MECOM 0 0 1 0 0 1
MEN1 1 0 0 0 0 1
MLH1 0 0 1 0 0 1
MSH6 0 0 1 0 0 1
MYB, NFIB 1 0 0 0 0 1
MYBL1, NFIB 1 0 0 0 0 1
RAD52 0 0 1 0 0 1
SATB1 1 0 0 0 0 1
SMARCA2 0 0 1 0 0 1
SMARCA4 0 0 1 0 0 1
SMARCB1 0 0 1 0 0 1
STAT3 0 0 1 0 0 1
STK11 0 0 1 0 0 1

Submitter and significance breakdown #

Total submitters: 15
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign total
Baylor Genetics 43 28 42 0 0 113
Database of Curated Mutations (DoCM) 0 100 0 0 0 100
Fulgent Genetics, Fulgent Genetics 14 5 20 25 4 68
Genome Sciences Centre, British Columbia Cancer Agency 3 6 21 0 0 30
Key Laboratory of Carcinogenesis and Cancer Invasion, Central South University 0 19 0 0 0 19
OMIM 7 0 0 0 0 7
Institute of Human Genetics Munich, Klinikum Rechts Der Isar, TU München 7 0 0 0 0 7
Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center 3 1 1 1 0 6
Ute Scholl Laboratory, Heinrich Heine University Duesseldorf 5 0 0 0 0 5
Donald Williams Parsons Laboratory, Baylor College of Medicine 0 1 0 0 0 1
Centre for Mendelian Genomics, University Medical Centre Ljubljana 0 0 1 0 0 1
Diagnostics Services (NGS), CSIR - Centre For Cellular And Molecular Biology 0 1 0 0 0 1
Genome-Nilou Lab 1 0 0 0 0 1
Suma Genomics 1 0 0 0 0 1
Neuberg Centre For Genomic Medicine, NCGM 0 0 1 0 0 1

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