ClinVar Miner

Variants in gene WNK1 with conflicting interpretations

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Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission Variants with at least 2 submissions and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any kind of conflict
334 140 2 26 18 0 1 43

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 2 0 0 0 0
likely pathogenic 0 0 1 0 0
uncertain significance 0 1 0 17 5
likely benign 0 0 17 0 26
benign 0 0 5 26 0

All variants with conflicting interpretations #

Total variants: 43
Download table as spreadsheet
NM_018979.4(WNK1):c.1074C>T (p.Thr358=) rs72648621
NM_018979.4(WNK1):c.108G>C (p.Gly36=) rs375485682
NM_018979.4(WNK1):c.1434C>T (p.Phe478=) rs61736906
NM_018979.4(WNK1):c.1512A>G (p.Leu504=) rs56325964
NM_018979.4(WNK1):c.1526T>C (p.Ile509Thr) rs34728563
NM_018979.4(WNK1):c.1855A>G (p.Thr619Ala) rs149388376
NM_018979.4(WNK1):c.2020A>G (p.Thr674Ala) rs11833299
NM_018979.4(WNK1):c.2052A>G (p.Ala684=) rs72648690
NM_018979.4(WNK1):c.2081T>C (p.Ile694Thr) rs61736905
NM_018979.4(WNK1):c.2139+2852C>T rs786205473
NM_018979.4(WNK1):c.2139+2872T>C rs72649808
NM_018979.4(WNK1):c.2139+3062C>T rs72649848
NM_018979.4(WNK1):c.2140-2493C>T rs111033590
NM_018979.4(WNK1):c.2140-2518dup rs137852735
NM_018979.4(WNK1):c.2140-3135T>C rs72649855
NM_018979.4(WNK1):c.2206A>G (p.Ile736Val) rs147099510
NM_018979.4(WNK1):c.2336C>T (p.Ala779Val) rs141428612
NM_018979.4(WNK1):c.2401A>G (p.Ile801Val) rs139449198
NM_018979.4(WNK1):c.2468A>G (p.His823Arg) rs56015776
NM_018979.4(WNK1):c.2490G>A (p.Pro830=) rs79816263
NM_018979.4(WNK1):c.2652G>A (p.Ala884=) rs142528714
NM_018979.4(WNK1):c.2664A>G (p.Val888=) rs769020140
NM_018979.4(WNK1):c.3490-5T>A rs72650719
NM_018979.4(WNK1):c.3516A>G (p.Ile1172Met) rs150532648
NM_018979.4(WNK1):c.3578G>A (p.Ser1193Asn) rs72650720
NM_018979.4(WNK1):c.3654A>G (p.Ser1218=) rs141971833
NM_018979.4(WNK1):c.4354A>G (p.Thr1452Ala) rs142543401
NM_018979.4(WNK1):c.446C>T (p.Ala149Val) rs34880640
NM_018979.4(WNK1):c.4605_4607del (p.Ser1536del) rs72650732
NM_018979.4(WNK1):c.4983T>C (p.Ser1661=) rs149852592
NM_018979.4(WNK1):c.5281-4G>A rs72650740
NM_018979.4(WNK1):c.5481A>G (p.Thr1827=) rs61736908
NM_018979.4(WNK1):c.5496G>A (p.Gln1832=) rs138219481
NM_018979.4(WNK1):c.5542_5550del (p.Thr1848_Ser1850del) rs544395150
NM_018979.4(WNK1):c.5583+3A>G rs72650758
NM_018979.4(WNK1):c.5734A>C (p.Ile1912Leu) rs201995891
NM_018979.4(WNK1):c.578C>A (p.Pro193Gln) rs72647372
NM_018979.4(WNK1):c.5833C>T (p.Arg1945Cys) rs117016551
NM_018979.4(WNK1):c.5991G>A (p.Glu1997=) rs61736907
NM_018979.4(WNK1):c.6150T>C (p.Leu2050=) rs151331381
NM_018979.4(WNK1):c.6624C>A (p.Ser2208Arg) rs72650768
NM_018979.4(WNK1):c.684C>T (p.Gly228=) rs72647374
NM_018979.4(WNK1):c.7021G>A (p.Gly2341Ser) rs146042595

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