ClinVar Miner

Variants in gene LYST with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:
ClinVar version:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic)
Variants with a confidence conflict
(e.g. benign vs likely benign)
Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects)
Variants with a clinically significant conflict
(e.g. benign vs pathogenic)
Variants with any conflict
807 88 4 13 43 0 4 58

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 4 1 2 0 0
likely pathogenic 1 0 2 0 0
uncertain significance 2 2 0 36 12
likely benign 0 0 36 0 12
benign 0 0 12 12 0

All variants with conflicting interpretations #

Total variants: 58
Download table as spreadsheet
HGVS dbSNP
NM_000081.4(LYST):c.10758C>T (p.Cys3586=) rs145136281
NM_000081.4(LYST):c.11229A>G (p.Arg3743=)
NM_000081.4(LYST):c.2150A>G (p.Asn717Ser) rs201255245
NM_000081.4(LYST):c.4006+8G>A rs369153654
NM_000081.4(LYST):c.4548C>T (p.Ser1516=) rs116551057
NM_000081.4(LYST):c.7137A>C (p.Leu2379=) rs61738992
NM_000081.4(LYST):c.7911G>A (p.Thr2637=) rs140229368
NM_000081.4(LYST):c.9244T>C (p.Leu3082=)
NM_000081.4(LYST):c.9990G>A (p.Ala3330=)
NM_000081.4(LYST):c.9C>T (p.Thr3=) rs33998267
NM_001301365.1(LYST):c.-5C>T rs141317482
NM_001301365.1(LYST):c.10127A>G (p.Asn3376Ser)
NM_001301365.1(LYST):c.10221C>T (p.Tyr3407=) rs146457386
NM_001301365.1(LYST):c.10477T>C (p.Phe3493Leu) rs200511787
NM_001301365.1(LYST):c.10800+4G>T rs41308172
NM_001301365.1(LYST):c.10941-7C>A rs72761794
NM_001301365.1(LYST):c.11268-5del rs36014994
NM_001301365.1(LYST):c.1467del (p.Glu489fs) rs80338644
NM_001301365.1(LYST):c.1494A>G (p.Arg498=) rs201412615
NM_001301365.1(LYST):c.1655T>C (p.Val552Ala) rs199617821
NM_001301365.1(LYST):c.1664A>C (p.His555Pro)
NM_001301365.1(LYST):c.196T>C (p.Leu66=) rs138393416
NM_001301365.1(LYST):c.2313G>A (p.Gln771=) rs147220685
NM_001301365.1(LYST):c.2363+10dup
NM_001301365.1(LYST):c.2363+4T>C rs201398337
NM_001301365.1(LYST):c.2413del (p.Glu805fs)
NM_001301365.1(LYST):c.2517T>C (p.Ile839=) rs78172154
NM_001301365.1(LYST):c.2700A>G (p.Leu900=) rs111463684
NM_001301365.1(LYST):c.2724C>T (p.Cys908=) rs201440611
NM_001301365.1(LYST):c.2754G>A (p.Glu918=) rs373577384
NM_001301365.1(LYST):c.281C>T (p.Thr94Ile) rs777389303
NM_001301365.1(LYST):c.2946T>C (p.Tyr982=) rs145892183
NM_001301365.1(LYST):c.3030A>G (p.Gly1010=) rs751511204
NM_001301365.1(LYST):c.3085C>T (p.Gln1029Ter) rs80338651
NM_001301365.1(LYST):c.3310C>T (p.Arg1104Ter) rs80338652
NM_001301365.1(LYST):c.3683A>G (p.Asn1228Ser) rs145553827
NM_001301365.1(LYST):c.368A>G (p.His123Arg) rs3768067
NM_001301365.1(LYST):c.3898A>G (p.Ile1300Val)
NM_001301365.1(LYST):c.4337G>A (p.Arg1446Gln) rs111722949
NM_001301365.1(LYST):c.4566A>C (p.Ala1522=) rs142344106
NM_001301365.1(LYST):c.5461-13dup rs557545474
NM_001301365.1(LYST):c.5518T>G (p.Ser1840Ala) rs115330112
NM_001301365.1(LYST):c.5635-4A>G rs754201076
NM_001301365.1(LYST):c.5719A>G (p.Ile1907Val)
NM_001301365.1(LYST):c.6291C>T (p.Ala2097=) rs199857997
NM_001301365.1(LYST):c.6292G>A (p.Ala2098Thr) rs146091043
NM_001301365.1(LYST):c.6482A>C (p.Glu2161Ala) rs147756847
NM_001301365.1(LYST):c.6710A>C (p.Gln2237Pro) rs138443479
NM_001301365.1(LYST):c.7368T>C (p.Asn2456=) rs199631995
NM_001301365.1(LYST):c.7506A>G (p.Gln2502=) rs140434436
NM_001301365.1(LYST):c.7780+2C>T rs760108842
NM_001301365.1(LYST):c.7806A>G (p.Gln2602=) rs372754364
NM_001301365.1(LYST):c.7862T>C (p.Met2621Thr) rs368500877
NM_001301365.1(LYST):c.7870C>T (p.Arg2624Trp) rs150306354
NM_001301365.1(LYST):c.8368A>C (p.Lys2790Gln) rs138506576
NM_001301365.1(LYST):c.8487C>T (p.Ile2829=) rs144597913
NM_001301365.1(LYST):c.8913T>G (p.Asn2971Lys) rs34702903
NM_001301365.1(LYST):c.9520G>A (p.Val3174Ile) rs199672291

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.